current user: public

anford Burnham Prebys Medical Discovery Institute
Please be advised that due to the planned maintenance our websites might be temporarily unavailable on December 17-18, 2018. We apologise for the inconvenience that this may cause.

PDB database is updated every Wednesday; Pfam database is updated monthly.

1).   Please paste one amino-acid sequence in fasta format (please sign in to submit more sequences and to store a list of your results)
2).   Sequences longer than 1000 aa should be split into (putative) domains.
3).   Examples of ffas server input and resulting ouput.

    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100

4).   Option: upload psi-blast result in text format to calculate the profile (otherwise psi-blast is run on the server)
 (can only be used for a single query sequence which provided in the text field above)

5).   Option: upload multiple sequence alignment in fasta format instead of submiting a single query sequence.

6).   Option: instead of submitting one protein sequence, please login to upload a protein sequence file in fasta format(<=100 sequences). Providing an email at login is required.

(We are limiting the bulk submission because of abuse. If you need to run entire genomes, please contact us )

7).   Option: check this box to include additional metagenomic data in the database used to calculate protein profile.

Select database(s) to be searched, and click Search (to select multiple databases click while holding down the CTRL key):
Databases of profiles:
(New: you can select some database(s) at first and search other databases within the same job later)
FFAS is supported by the NIH grant R01-GM087218-01
1 2 0 3 1 4   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.