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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|16127995|ref|NP_414542.1| thr operon leader peptide (thrL b0001 exp) [Escherichia coli str. K-12 substr. MG1655] 21 COG0516 1-21 -3.790 28  [N] COG5567 Predicted small periplasmic lipoprotein
H.sapiens 1-18 -4.690 27  sp|Q9C0D2|K1731_HUMAN Leucine-rich repeat-containing protein KIAA1731 OS=Homo sapiens GN=KIAA1731 PE=2 SV=4 (Range: 1951-2250)
HGM_OVER 1-20 -3.030 15  PB045072 _Gut.Meta.Jp.0111663_ gi|163310555|dbj|BABD01000145.1||3 (+ 1662:2028~0 complete)
JCSG0516 1-19 -6.530 21  SP18373A NP_372525.1 413697 Purified-2010-09-29
NEW_HUMAN_DOMAINS 3-20 -3.130 16  sp|Q96JI7|SPTCS_HUMAN Spatacsin OS=Homo sapiens GN=SPG11 PE=1 SV=3 (Range: 261-390)
PDB0516 3-16 -4.290 50  1vry_A mol:protein length:76 Glycine receptor alpha-1 chain
PfamA30U 1-11 -2.750 36  PF10471.7; C1HA50_PARBA/1-73; Anaphase-promoting complex APC subunit CDC26
SCOP206 1-21 -1.360 19  d2piha1 a.281.1.1 (A:2-124) Uncharacterized protein YmcA {Bacillus subtilis [TaxId: 1423]}
VFDB 1-16 -2.540 31  VFG016263(gi:30021216) (hblC) Hemolysin BL lytic component L2 [HBL (VF0532)] [Bacillus cereus ATCC 14579]
2 gi|16127996|ref|NP_414543.1| fused aspartokinase I and homoserine dehydrogenase I (thrA b0002 exp) [Escherichia coli str. K-12 substr. MG1655] 820 COG0516 1-483 -108.000 26  [E] COG0527 Aspartokinases
456-820 -114.000 67  [E] COG0460 Homoserine dehydrogenase
H.sapiens 119-383 -8.440 11  sp|P54886|P5CS_HUMAN Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens GN=ALDH18A1 PE=1 SV=2 (Range: 151-450)
HGM_OVER 434-706 -3.190 PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;
JCSG0516 1-477 -89.700 20  MJ8463A YP_957443.1 403171 Crystal|NMR-2009-10-31
465-815 -44.900 23  FN12420A NP_978932.1 379029 Purified-2007-08-28
NEW_HUMAN_DOMAINS 189-272 -5.700 19  sp|Q9BYP7|WNK3_HUMAN Serine/threonine-protein kinase WNK3 OS=Homo sapiens GN=WNK3 PE=1 SV=3 (Range: 1721-1800)
PDB0516 1-465 -113.000 36  3c1m_A mol:protein length:473 Probable aspartokinase
461-817 -99.800 32  1q7g_A mol:protein length:359 Homoserine dehydrogenase
PfamA30U 614-811 -29.800 28  PF00742.17; R5EAW4_9BURK/138-316; Homoserine dehydrogenase
SCOP206 3-300 -81.700 35  d3c1ma1 c.73.1.3 (A:2-303) automated matches {Methanocaldococcus jannaschii [TaxId: 2190]}
315-381 -28.500 34  d3c1ma3 d.58.18.0 (A:404-470) automated matches {Methanocaldococcus jannaschii [TaxId: 2190]}
382-477 -36.200 24  d3c1ma2 d.58.18.0 (A:304-403) automated matches {Methanocaldococcus jannaschii [TaxId: 2190]}
462-635 -58.800 25  d1ebfa1 c.2.1.3 (A:2-150,A:341-359) Homoserine dehydrogenase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
614-798 -77.700 36  d1ebfa2 d.81.1.2 (A:151-340) Homoserine dehydrogenase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
VFDB 162-804 -6.090 10  VFG000184(gi:15598301) (xcpQ) general secretion pathway protein D [xcp secretion system (VF0084)] [Pseudomonas aeruginosa PAO1]
3 gi|16127997|ref|NP_414544.1| homoserine kinase (thrB b0003 exp) [Escherichia coli str. K-12 substr. MG1655] 310 COG0516 2-310 -111.000 71  [E] COG0083 Homoserine kinase
H.sapiens 1-286 -21.500 15  sp|Q8N0W3|FUK_HUMAN L-fucose kinase OS=Homo sapiens GN=FUK PE=2 SV=2 (Range: 751-1050)
HGM_OVER 110-303 -2.700 PB002776 gi|157737147|ref|YP_001489830.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]gi|157699001|gb|ABV67161.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]
JCSG0516 2-309 -92.200 26  TM0545 TM0545 282418 Purified-2001-12-06
NEW_HUMAN_DOMAINS 180-263 -6.100 13  tr|E9PFE0|E9PFE0_HUMAN Uncharacterized protein OS=Homo sapiens GN=CIITA PE=4 SV=1 (Range: 286-365)
PDB0516 1-309 -118.000 76  4rpf_A mol:protein length:310 Homoserine kinase
PfamA30U 83-150 -13.200 25  PF00288.24; ISPE_BACSU/86-144; GHMP kinases N terminal domain
SCOP206 2-167 -65.900 31  d1h72c1 d.14.1.5 (C:5-167) Homoserine kinase {Methanococcus jannaschii [TaxId: 2190]}
170-308 -54.400 28  d1h72c2 d.58.26.1 (C:168-300) Homoserine kinase {Methanococcus jannaschii [TaxId: 2190]}
VFDB 1-309 -25.800 16  VFG001953(gi:15792743) (hddA) D-glycero-D-manno-heptose 7-phosphate kinase [Capsule (VF0323)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
4 gi|16127998|ref|NP_414545.1| threonine synthase (thrC b0004 exp) [Escherichia coli str. K-12 substr. MG1655] 428 COG0516 1-427 -105.000 29  [E] COG0498 Threonine synthase
H.sapiens 1-427 -96.800 29  sp|Q86YJ6|THNS2_HUMAN Threonine synthase-like 2 OS=Homo sapiens GN=THNSL2 PE=2 SV=3
HGM_OVER 125-329 -3.650 11  PB155142 _HOMD.0127537_ bfor_c_1_1790 Tannerella forsythia ATCC 43037 [677748 - 680894] ORF
JCSG0516 63-405 -21.900 23  TM0546 TM0546 282419 Purified-2001-10-17
NEW_HUMAN_DOMAINS 127-215 -4.430 23  sp|Q92736|RYR2_HUMAN Ryanodine receptor 2 OS=Homo sapiens GN=RYR2 PE=1 SV=3 (Range: 3741-3827)
PDB0516 1-428 -131.000 100  1vb3_A mol:protein length:428 Threonine synthase
PfamA30U 2-80 -36.400 32  PF14821.4; Q21LF7_SACD2/2-80; Threonine synthase N terminus
SCOP206 1-428 -131.000 100  d1vb3a1 c.79.1.1 (A:1-428) Threonine synthase {Escherichia coli [TaxId: 562]}
VFDB 29-254 -4.490 11  VFG041341(gi:52842733) (lpg2525) Dot/Icm type IV secretion system effector [Dot/Icm (SS047)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
5 gi|16127999|ref|NP_414546.1|(removed signal:1-23) predicted protein (yaaX b0005 exp) [Escherichia coli str. K-12 substr. MG1655] 75 COG0516 1-44 -7.070 19  [S] COG4950 Uncharacterized protein conserved in bacteria
H.sapiens 10-31 -11.900 31  sp|Q14517|FAT1_HUMAN(removed signalp:1-21) Protocadherin Fat 1 OS=Homo sapiens GN=FAT1 PE=1 SV=1 (Range: 4351-4569)
HGM_OVER 3-27 -4.260 16  PB002104 Q72PH8_LEPIC/1-220 PB002104; Pfam-B_2104;
JCSG0516 1-75 -42.800 97  SP18461C NP_285697.1 410853 Selected-2009-11-12
NEW_HUMAN_DOMAINS 17-31 -8.270 40  sp|Q14517|FAT1_HUMAN Protocadherin Fat 1 OS=Homo sapiens GN=FAT1 PE=1 SV=2 (Range: 4376-4456)
PDB0516 3-34 -9.440 23  3chx_B mol:protein length:252 PmoA
PfamA30U 2-75 -34.300 31  PF10697.7; Q0WCT3_YERPE/39-126; Protein of unknown function (DUF2502 topsan)
SCOP206 1-38 -7.180 15  d4j9fa_ b.34.2.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-44 -5.840 27  VFG042439(gi:5523850) (afaE-VII) adhesin AfaE-VII [Afimbrial adhesin, AFA-VII (AI014)] [Escherichia coli str. 239 KH 89]
6 gi|16128000|ref|NP_414547.1| conserved protein, UPF0246 family (yaaA b0006 exp) [Escherichia coli str. K-12 substr. MG1655] 258 COG0516 1-258 -129.000 99  [S] COG3022 Uncharacterized protein conserved in bacteria
H.sapiens 26-237 -7.520 sp|O15033|K0317_HUMAN(removed signalp:1-31) Protein KIAA0317 OS=Homo sapiens GN=KIAA0317 PE=2 SV=3 (Range: 301-600)
HGM_OVER 10-203 -5.070 15  PB007147 Q11UU2_CYTH3/1-245 PB007147; Pfam-B_7147;
JCSG0516 23-218 -6.380 14  PS05988 NP_519234.1 376593 Purified-2007-11-08
NEW_HUMAN_DOMAINS 115-236 -6.840 19  sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapiens GN=LARP1 PE=1 SV=2 (Range: 877-1043)
PDB0516 1-258 -126.000 100  5caj_A mol:protein length:278 UPF0246 protein YaaA
PfamA30U 1-243 -124.000 60  PF03883.12; D4ZH13_SHEVD/1-244; Peroxide stress protein YaaA
SCOP206 112-220 -7.290 20  d2ofca_ b.97.1.2 (A:) automated matches {Athelia rolfsii [TaxId: 39291]}
VFDB 110-218 -5.670 14  VFG002423(gi:151222088) (scn) complement inhibitor SCIN [SCIN (VF0425)] [Staphylococcus aureus subsp. aureus str. Newman]
7 gi|16128001|ref|NP_414548.1| predicted transporter (yaaJ b0007 exp) [Escherichia coli str. K-12 substr. MG1655] 476 COG0516 1-471 -134.000 41  [E] COG1115 Na+/alanine symporter
H.sapiens 52-437 -9.970 11  sp|Q9H598|VIAAT_HUMAN Vesicular inhibitory amino acid transporter OS=Homo sapiens GN=SLC32A1 PE=1 SV=2
HGM_OVER 16-344 -3.180 PB004476 gi|139436894|ref|ZP_01771054.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]gi|133776541|gb|EBA40361.1| Hypothetical protein COLAER_00025 [Collinsella aerofaciens ATCC 25986]
JCSG0516 16-428 -6.090 13  SP19117A NP_251051.1 413324 Selected-2009-11-12
NEW_HUMAN_DOMAINS 77-125 -6.890 18  sp|Q9Y4D8|K0614_HUMAN Probable E3 ubiquitin-protein ligase C12orf51 OS=Homo sapiens GN=C12orf51 PE=1 SV=5 (Range: 1-60)
PDB0516 52-432 -12.900 15  3gi8_C mol:protein length:444 Uncharacterized protein MJ0609
PfamA30U 47-453 -118.000 46  PF01235.15; C5DAE3_GEOSW/49-446; Sodium:alanine symporter family
SCOP206 59-427 -8.640 13  d2a65a1 f.54.1.1 (A:5-513) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
VFDB 16-286 -4.540 11  VFG001850(gi:52842892) (dotA) Dot/Icm type IV secretion system protein DotA [Dot/Icm (VF0156)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
8 gi|16128002|ref|NP_414549.1| transaldolase B (talB b0008 exp) [Escherichia coli str. K-12 substr. MG1655] 317 COG0516 1-317 -154.000 89  [G] COG0176 Transaldolase
H.sapiens 1-317 -145.000 59  sp|P37837|TALDO_HUMAN Transaldolase OS=Homo sapiens GN=TALDO1 PE=1 SV=2
HGM_OVER 89-194 -2.900 16  PB044863 Q5LB69_BACFN/1-105 PB044863; Pfam-B_44863;
JCSG0516 1-317 -145.000 59  MA0295A 13435797 399843 Cloned-2009-01-23
NEW_HUMAN_DOMAINS 137-235 -7.350 sp|Q9H2P0|ADNP_HUMAN Activity-dependent neuroprotector homeobox protein OS=Homo sapiens GN=ADNP PE=1 SV=1 (Range: 446-529)
PDB0516 1-317 -150.000 99  3cwn_A mol:protein length:337 Transaldolase B
PfamA30U 14-313 -146.000 58  PF00923.17; Q966C7_CAEEL/13-315; Transaldolase/Fructose-6-phosphate aldolase
SCOP206 2-317 -153.000 99  d3cwna_ c.1.10.1 (A:) automated matches {Escherichia coli [TaxId: 562]}
VFDB 20-251 -8.020 11  VFG043390(gi:15646189) (pdxJ) pyridoxine 5`-phosphate synthase [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
9 gi|16128003|ref|NP_414550.1| molybdochelatase incorporating molybdenum into molybdopterin (mog b0009 exp) [Escherichia coli str. K-12 substr. MG1655] 195 COG0516 2-191 -102.000 77  [H] COG0521 Molybdopterin biosynthesis enzymes
H.sapiens 2-194 -78.200 33  sp|Q9NQX3|GEPH_HUMAN Gephyrin OS=Homo sapiens GN=GPHN PE=1 SV=1 (Range: 1-300)
HGM_OVER 98-151 -2.650 18  HGC00933 gi|162753228|dbj|BAAZ01012194.1|2.0 TMP01261;
JCSG0516 1-142 -13.600 22  GE7651A YP_001088583.1 396890 Crystal|NMR-2009-07-18
NEW_HUMAN_DOMAINS 88-171 -4.720 20  sp|Q86UP3|ZFHX4_HUMAN Zinc finger homeobox protein 4 OS=Homo sapiens GN=ZFHX4 PE=1 SV=1 (Range: 3173-3262)
PDB0516 1-195 -105.000 99  1di6_A mol:protein length:195 MOLYBDENUM COFACTOR BIOSYNTHETIC ENZYME
PfamA30U 8-144 -17.400 21  PF00994.22; CINAL_DESPS/4-169; Probable molybdopterin binding domain
SCOP206 2-191 -102.000 99  d1di6a_ c.57.1.1 (A:) MogA {Escherichia coli [TaxId: 562]}
VFDB 46-147 -6.420 15  VFG001225(gi:15595605) (pilG) twitching motility protein PilG [Type IV pili (VF0082)] [Pseudomonas aeruginosa PAO1]
10 gi|16128004|ref|NP_414551.1| inner membrane protein, Grp1_Fun34_YaaH family (yaaH b0010 exp) [Escherichia coli str. K-12 substr. MG1655] 188 COG0516 3-184 -96.100 61  [S] COG1584 Predicted membrane protein
H.sapiens 22-184 -9.600 14  sp|Q8TF62|AT8B4_HUMAN Probable phospholipid-transporting ATPase IM OS=Homo sapiens GN=ATP8B4 PE=2 SV=3 (Range: 901-1192)
47-118 -9.630 18  sp|Q96HP8|T176A_HUMAN Transmembrane protein 176A OS=Homo sapiens GN=TMEM176A PE=2 SV=1
HGM_OVER 19-74 -6.620 16  PB003142 Q8DVS6_STRMU/1-162 PB003142; Pfam-B_3142;
JCSG0516 8-130 -7.240 15  TM1341 TM1341 283203 Purified-2001-12-19
NEW_HUMAN_DOMAINS 3-57 -5.830 18  sp|Q86XQ3|CTSR3_HUMAN Cation channel sperm-associated protein 3 OS=Homo sapiens GN=CATSPER3 PE=1 SV=1 (Range: 315-398)
PDB0516 14-123 -6.490 10  3pjs_K mol:protein length:166 Voltage-gated potassium channel
PfamA30U 3-187 -89.100 33  PF01184.17; A7TND9_VANPO/71-277; GPR1/FUN34/yaaH family
SCOP206 2-84 -7.330 22  d1e5da1 c.23.5.1 (A:251-402) Rubredoxin oxygen:oxidoreductase (ROO), C-terminal domain {Desulfovibrio gigas [TaxId: 879]}
VFDB 45-188 -5.930 13  VFG002151(gi:15605597) (copB2) Type III secretion system translocator CopB2 [TTSS (VF0344)] [Chlamydia trachomatis D/UW-3/CX]
11 gi|16128005|ref|NP_414552.1| conserved protein, UPF0174 family (yaaW b0011 exp) [Escherichia coli str. K-12 substr. MG1655] 237 COG0516 1-237 -87.500 100  [S] COG4735 Uncharacterized protein conserved in bacteria
H.sapiens 78-136 -8.140 17  sp|P52655|TF2AA_HUMAN Transcription initiation factor IIA subunit 1 OS=Homo sapiens GN=GTF2A1 PE=1 SV=1
HGM_OVER 18-124 -5.430 13  PB002794 gi|86143885|ref|ZP_01062253.1| hypothetical protein MED217_03525 [Flavobacterium sp. MED217]gi|85829592|gb|EAQ48055.1| hypothetical protein MED217_03525 [Leeuwenhoekiella blandensis MED217]
JCSG0516 3-142 -7.960 14  MG8793B YP_413069.1 391079 Purified-2008-09-03
NEW_HUMAN_DOMAINS 14-124 -5.440 11  sp|Q9ULG6|CCPG1_HUMAN Cell cycle progression protein 1 OS=Homo sapiens GN=CCPG1 PE=1 SV=3 (Range: 629-736)
PDB0516 73-136 -7.940 18  1rm1_C mol:protein length:286 Transcription initiation factor IIA large cha
PfamA30U 5-38 -10.600 29  PF13099.4; E3D0J1_9BACT/3-37; Domain of unknown function (DUF3944 topsan)
SCOP206 2-93 -6.490 13  d2mhra_ a.24.4.1 (A:) Myohemerythin {Sipunculan worm (Themiste zostericola) [TaxId: 6437]}
VFDB 1-132 -5.720 14  VFG006592(gi:15645645) (fliM) flagellar motor switch protein FliM [Pse5Ac7Ac (AI150)] [Helicobacter pylori 26695]
12 gi|16128007|ref|NP_414554.1|(removed signal:1-23) conserved protein, UPF0412 family (yaaI b0013 exp) [Escherichia coli str. K-12 substr. MG1655] 111 COG0516 29-100 -6.040 15  [R] COG4455 Protein of avirulence locus involved in temperature-dependent protein secretion
H.sapiens 7-111 -6.310 10  sp|Q8IWT3|CUL9_HUMAN Cullin-9 OS=Homo sapiens GN=CUL9 PE=1 SV=2 (Range: 1201-1500)
HGM_OVER 2-109 -6.880 PB029229 gi|150007903|ref|YP_001302646.1| hypothetical protein BDI_1263 [Parabacteroides distasonis ATCC 8503]gi|149936327|gb|ABR43024.1| conserved hypothetical protein [Parabacteroides distasonis ATCC 8503]
JCSG0516 1-111 -56.900 80  GS13914A YP_001333704.1 384834 Purified-2010-04-01
NEW_HUMAN_DOMAINS 31-109 -6.270 tr|C9J1H5|C9J1H5_HUMAN Uncharacterized protein OS=Homo sapiens GN=TCTN1 PE=4 SV=1 (Range: 328-483)
PDB0516 36-111 -7.880 12  4za1_A mol:protein length:151 NosA
PfamA30U 1-109 -55.500 79  PF10807.6; A6T4F3_KLEP7/3-132; Protein of unknown function (DUF2541 topsan)
SCOP206 31-97 -6.040 10  d1bu8a1 b.12.1.2 (A:337-449) Pancreatic lipase, C-terminal domain {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 1-110 -5.670 12  VFG000856(gi:22001088) (agg3B) invasin protein [AAFs (VF0214)] [Escherichia coli 55989]
13 gi|16128008|ref|NP_414555.1| chaperone Hsp70, co-chaperone with DnaJ (dnaK b0014 exp) [Escherichia coli str. K-12 substr. MG1655] 638 COG0516 1-638 -193.000 56  [O] COG0443 Molecular chaperone
H.sapiens 4-505 -125.000 31  sp|Q0VDF9|HSP7E_HUMAN Heat shock 70 kDa protein 14 OS=Homo sapiens GN=HSPA14 PE=1 SV=1
255-553 -123.000 63  sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial OS=Homo sapiens GN=HSPA9 PE=1 SV=2 (Range: 301-600)
405-630 -87.800 47  sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial OS=Homo sapiens GN=HSPA9 PE=1 SV=2 (Range: 451-679)
HGM_OVER 115-495 -4.420 12  PB162065 _Gut.Meta.Jp.0089312_ gi|162832207|dbj|BABA01012502.1||1 (- 0:1326~0 complete)
JCSG0516 1-614 -190.000 53  TM0373 TM0373 282248 Purified-2001-03-14
NEW_HUMAN_DOMAINS 382-502 -6.790 17  sp|O43301|HS12A_HUMAN Heat shock 70 kDa protein 12A OS=Homo sapiens GN=HSPA12A PE=1 SV=2 (Range: 520-675)
PDB0516 1-605 -210.000 99  2kho_A mol:protein length:605 Heat shock protein 70
1-638 -117.000 25  3d2e_A mol:protein length:675 Heat shock protein homolog SSE1
PfamA30U 4-604 -202.000 62  PF00012.18; HSP7E_DROME/54-653; Hsp70 protein
SCOP206 4-180 -73.300 33  d4gnia1 c.55.1.0 (A:13-196) automated matches {Chaetomium thermophilum [TaxId: 759272]}
183-382 -63.900 45  d3i33a2 c.55.1.1 (A:190-384) automated matches {Human (Homo sapiens) [TaxId: 9606]}
389-506 -75.100 100  d4f01a1 b.130.1.1 (A:389-506) automated matches {Escherichia coli K-12 [TaxId: 83333]}
507-602 -40.200 100  d4f01a2 a.8.4.1 (A:507-602) automated matches {Escherichia coli K-12 [TaxId: 83333]}
VFDB 3-404 -9.030 15  VFG010479(gi:52841162) (pilM) type IV pilus inner membrane platform protein PilM [type IV pili (AI111)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
14 gi|16128009|ref|NP_414556.1| chaperone Hsp40, co-chaperone with DnaK (dnaJ b0015 exp) [Escherichia coli str. K-12 substr. MG1655] 376 COG0516 1-372 -139.000 59  [O] COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain
H.sapiens 1-373 -124.000 34  sp|Q96EY1|DNJA3_HUMAN(removed signalp:1-21) DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens GN=DNAJA3 PE=1 SV=2
HGM_OVER 291-376 -5.470 16  HGC00928 gi|162868028|dbj|BABB01001979.1|3.0 TMP01255;
JCSG0516 1-353 -130.000 40  TM0849 TM0849 282719 Selected-2001-10-12
NEW_HUMAN_DOMAINS 108-200 -6.470 20  sp|Q5T197|DCST1_HUMAN DC-STAMP domain-containing protein 1 OS=Homo sapiens GN=DCST1 PE=2 SV=1 (Range: 596-684)
PDB0516 1-360 -85.500 39  3lz8_A mol:protein length:329 Putative chaperone DnaJ
PfamA30U 5-67 -38.900 54  PF00226.29; Q22028_CAEEL/17-79; DnaJ domain
117-330 -84.600 34  PF01556.16; T0NBZ6_9EURY/129-343; DnaJ C terminal domain
SCOP206 1-80 -45.800 37  d2yuaa1 a.2.3.0 (A:8-93) automated matches {Human (Homo sapiens) [TaxId: 9606]}
2-111 -34.000 18  d1gh6a_ a.2.3.1 (A:) Large T antigen, the N-terminal J domain {Simian virus 40, Sv40 [TaxId: 10633]}
131-209 -44.300 100  d1exka_ g.54.1.1 (A:) Cysteine-rich domain of the chaperone protein DnaJ {Escherichia coli [TaxId: 562]}
187-254 -13.700 27  d2q2ga1 b.4.1.0 (A:4-86) automated matches {Cryptosporidium parvum [TaxId: 353152]}
255-344 -20.400 25  d3agxa2 b.4.1.0 (A:246-340) automated matches {Human (Homo sapiens) [TaxId: 9606]}
VFDB 40-215 -5.470 14  VFG002358(gi:123442806) (flhC) flagellar biosynthesis transcription activator FlhC [Flagella (VF0394)] [Yersinia enterocolitica subsp. enterocolitica 8081]
15 gi|16128010|ref|NP_414557.1| IS186 transposase (insL b0016 exp) [Escherichia coli str. K-12 substr. MG1655] 370 COG0516 1-361 -70.300 17  [L] COG3385 FOG: Transposase and inactivated derivatives
H.sapiens 10-370 -8.270 sp|Q8N328|PGBD3_HUMAN PiggyBac transposable element-derived protein 3 OS=Homo sapiens GN=PGBD3 PE=2 SV=3
HGM_OVER 324-370 -17.200 12  HGC00857 gi|162620543|dbj|BAAW01002606.1|2.0 TMP01139;
JCSG0516 10-352 -10.800 14  TT7869C NP_718826.1 404150 Selected-2009-08-14
NEW_HUMAN_DOMAINS 285-343 -5.510 17  sp|Q5T011|SZT2_HUMAN Protein SZT2 OS=Homo sapiens GN=SZT2 PE=2 SV=3 (Range: 2648-2731)
PDB0516 1-359 -27.400 12  1mm8_A mol:protein length:481 Tn5 Transposase
PfamA30U 4-354 -30.900 12  PF04693.10; Q5MPE9_9CREN/3-342; Archaeal putative transposase ISC1217
SCOP206 34-359 -26.300 12  d1musa1 c.55.3.4 (A:4-476) Transposase inhibitor (Tn5 transposase) {Escherichia coli [TaxId: 562]}
VFDB 279-324 -5.980 13  VFG041906(gi:28901218) (VPA1363) type III secretion system chaperone [T3SS2 (VF0409)] [Vibrio parahaemolyticus RIMD 2210633]
16 gi|16128012|ref|NP_414559.1| regulatory protein for HokC, overlaps CDS of hokC (mokC b0018 exp) [Escherichia coli str. K-12 substr. MG1655] 69 COG0516 15-43 -6.650 30  [S] COG3430 Uncharacterized protein conserved in archaea
H.sapiens 26-54 -9.330 17  sp|P22794|EVI2A_HUMAN(removed signalp:1-30) Protein EVI2A OS=Homo sapiens GN=EVI2A PE=2 SV=2
HGM_OVER 20-50 -5.560 20  PB019279 Q5LE73_BACFN/1-147 PB019279; Pfam-B_19279;
JCSG0516 17-47 -10.800 19  SP16841A ZP_02037722.1 407172 Purified-2010-09-29
NEW_HUMAN_DOMAINS 23-57 -7.420 14  sp|Q9Y2G1|MRF_HUMAN Myelin gene regulatory factor OS=Homo sapiens GN=MRF PE=1 SV=3 (Range: 758-829)
PDB0516 23-47 -5.000 12  3dl8_E mol:protein length:107 Protein-export membrane protein secG
PfamA30U 26-66 -30.400 43  PF01848.14; A8GAB3_SERP5/6-46; Hok/gef family
SCOP206 30-69 -4.870 11  d1q25a1 b.64.1.1 (A:7-129) Cation-independent mannose-6-phosphate receptor (MIR-receptor) {Cow (Bos taurus) [TaxId: 9913]}
VFDB 1-68 -7.400 12  VFG036884(gi:15676785) (pilK) pilin-like protein may involving in pseudopilus formation [Type IV pili (CVF189)] [Neisseria meningitidis MC58]
17 gi|49175991|ref|YP_025292.1| toxic membrane protein, small (hokC b4412 exp) [Escherichia coli str. K-12 substr. MG1655] 50 COG0516 16-50 -5.290 [W] KOG3544 Collagens (type IV and type XIII), and related proteins
H.sapiens 7-35 -8.520 17  sp|P22794|EVI2A_HUMAN(removed signalp:1-30) Protein EVI2A OS=Homo sapiens GN=EVI2A PE=2 SV=2
HGM_OVER 1-31 -5.060 20  PB019279 Q5LE73_BACFN/1-147 PB019279; Pfam-B_19279;
JCSG0516 1-28 -9.090 17  SP16841A ZP_02037722.1 407172 Purified-2010-09-29
NEW_HUMAN_DOMAINS 4-38 -6.230 14  sp|Q9Y2G1|MRF_HUMAN Myelin gene regulatory factor OS=Homo sapiens GN=MRF PE=1 SV=3 (Range: 758-829)
PDB0516 1-27 -4.370 11  1s5l_I mol:protein length:38 Photosystem II reaction center I protein
PfamA30U 7-47 -30.800 43  PF01848.14; A8GAB3_SERP5/6-46; Hok/gef family
SCOP206 1-27 -4.410 11  d3wu2i_ f.23.37.1 (I:) Photosystem II reaction center protein I, PsbI {Thermosynechococcus vulcanus [TaxId: 32053]}
VFDB 6-49 -5.440 20  VFG042862(gi:52840866) (pilX) type IV pilus assembly protein PilX [type IV pili (AI111)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
18 gi|16128013|ref|NP_414560.1| sodium-proton antiporter (nhaA b0019 exp) [Escherichia coli str. K-12 substr. MG1655] 388 COG0516 1-388 -122.000 100  [P] COG3004 Na+/H+ antiporter
H.sapiens 18-375 -7.450 13  sp|Q86UD5|NHDC2_HUMAN Mitochondrial sodium/hydrogen exchanger NHA2 OS=Homo sapiens GN=NHEDC2 PE=1 SV=2
HGM_OVER 64-159 -2.760 12  PB078508 A6TV41_9CLOT/1-155 PB078508; Pfam-B_78508;
JCSG0516 57-385 -4.890 15  MA16097A NP_775897.2 400084 Purified-2009-03-27
NEW_HUMAN_DOMAINS 68-180 -5.310 15  sp|Q15042|RB3GP_HUMAN Rab3 GTPase-activating protein catalytic subunit OS=Homo sapiens GN=RAB3GAP1 PE=1 SV=3 (Range: 101-315)
PDB0516 1-387 -117.000 99  4atv_A mol:protein length:401 NA(+)/H(+) ANTIPORTER NHAA
PfamA30U 5-380 -121.000 100  PF06965.10; NHAA_ECOLI/5-380; Na+/H+ antiporter 1
SCOP206 41-241 -5.920 12  d1ikpa1 b.29.1.7 (A:2-251) Exotoxin A, N-terminal domain {Pseudomonas aeruginosa [TaxId: 287]}
VFDB 38-172 -5.270 17  VFG021840(gi:15608487) (mbtK) Lysine N-acetyltransferase MbtK [mycobactin (IA031)] [Mycobacterium tuberculosis H37Rv]
19 gi|16128014|ref|NP_414561.1| DNA-binding transcriptional activator (nhaR b0020 exp) [Escherichia coli str. K-12 substr. MG1655] 301 COG0516 3-299 -47.000 16  [K] COG0583 Transcriptional regulator
H.sapiens 4-91 -7.000 14  sp|O60313|OPA1_HUMAN Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens GN=OPA1 PE=1 SV=3 (Range: 751-960)
HGM_OVER 7-146 -4.030 PB007733 A3U921_9FLAO/1-209 PB007733; Pfam-B_7733;
JCSG0516 3-300 -98.400 26  MJ10038I NP_902892.1 402605 Purified-2009-11-14
NEW_HUMAN_DOMAINS 4-91 -7.540 14  sp|O60313|OPA1_HUMAN Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens GN=OPA1 PE=1 SV=3 (Range: 825-960)
PDB0516 3-301 -64.900 15  3fzv_A mol:protein length:306 Probable transcriptional regulator
PfamA30U 13-66 -20.900 29  PF00126.25; Q8EIK0_SHEON/8-63; Bacterial regulatory helix-turn-helix protein, lysR family
90-295 -19.900 11  PF03466.18; Q98I60_RHILO/88-294; LysR substrate binding domain
SCOP206 6-91 -37.700 27  d1ixca1 a.4.5.37 (A:1-89) LysR-type regulatory protein CbnR {Ralstonia eutropha [TaxId: 106590]}
90-295 -36.700 11  d2fyia1 c.94.1.1 (A:88-307) LysR-type regulatory protein Cbl {Escherichia coli [TaxId: 562]}
VFDB 3-299 -64.400 14  VFG000441(gi:17233493) (spvR) Salmonella plasmid virulence: regulation of spv operon, lysR family [Spv (VF0107)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]
20 gi|16128015|ref|NP_414562.1| IS1 transposase B (insB b0021 exp) [Escherichia coli str. K-12 substr. MG1655] 167 COG0516 4-167 -13.500 11  [L] COG3676 Transposase and inactivated derivatives
48-167 -72.100 28  [L] COG1662 Transposase and inactivated derivatives, IS1 family
H.sapiens 48-165 -9.210 20  sp|Q9QC07|POK7_HUMAN HERV-K_1q23.3 provirus ancestral Pol protein OS=Homo sapiens PE=3 SV=2 (Range: 601-812)
HGM_OVER 51-162 -4.090 11  PB000821 Q82P27_STRAW/1-209 PB000821; Pfam-B_821;
JCSG0516 43-167 -13.700 13  GD14004A RER070207002105 388710 Selected-2007-09-21
NEW_HUMAN_DOMAINS 1-147 -6.080 14  sp|Q8IY17|PLPL6_HUMAN Neuropathy target esterase OS=Homo sapiens GN=PNPLA6 PE=1 SV=2 (Range: 774-969)
PDB0516 2-166 -10.600 10  4fw2_A mol:protein length:270 Integrase
44-158 -13.300 14  3kkr_A mol:protein length:152 Integrase
PfamA30U 37-167 -86.700 99  PF03400.11; Q32H87_SHIDS/20-150; IS1 transposase
SCOP206 46-158 -12.500 15  d3kkra1 c.55.3.0 (A:60-208) automated matches {Bovine immunodeficiency virus [TaxId: 417296]}
VFDB 39-141 -7.620 11  VFG002460(gi:53722563) (bsaR) Type III secretion system protein BsaR [Bsa T3SS (VF0428)] [Burkholderia pseudomallei K96243]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Li W, Pio F, Pawlowski K, Godzik A. Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology. Bioinformatics. 2000 Dec;16(12):1105-10.