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# Query Length Result vs. Range Score %id Covered by template(s)
1 gi|6319249|ref|NP_009332.1|(removed signalp:1-20) hypothetical protein; Pau8p (YAL068C) [Saccharomyces cerevisiae] 100 COG0516 13-99 -6.620 14  [S] COG3309 Uncharacterized virulence-associated protein D
H.sapiens 10-83 -6.990 16  sp|P59093|CU099_HUMAN Uncharacterized protein C21orf99 OS=Homo sapiens GN=C21orf99 PE=2 SV=1
HGM_OVER 24-94 -4.750 PB025553 _HOMD.0078651_ pint_c_1_4510 Prevotella intermedia 17 [1755134 - 1755736] ORF
JCSG0516 9-81 -7.040 NN9114A NP_107265.1 400896 Cloned-2009-07-10
NEW_HUMAN_DOMAINS 8-92 -7.220 18  sp|Q9UKL3|C8AP2_HUMAN CASP8-associated protein 2 OS=Homo sapiens GN=CASP8AP2 PE=1 SV=1 (Range: 1021-1151)
PDB0516 1-91 -10.700 16  2jk1_A mol:protein length:139 HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEI
PfamA30U 2-95 -48.400 23  PF00660.15; E7KHT3_YEASA/13-116; Seripauperin and TIP1 family
SCOP206 1-91 -10.700 16  d2jk1a_ c.23.1.0 (A:) automated matches {Rhodobacter capsulatus [TaxId: 1061]}
VFDB 1-94 -5.730 VFG043206(gi:123442797) (cheY) chemotaxis regulatory protein CheY [peritrichous flagella (AI145)] [Yersinia enterocolitica subsp. enterocolitica 8081]
2 gi|33438754|ref|NP_878038.1| Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; Yal067w-ap (YAL067W-A) [Saccharomyces cerevisiae] 75 COG0516 3-75 -7.160 14  [R] KOG1533 Predicted GTPase
H.sapiens 1-65 -7.590 27  sp|O75064|DEN4B_HUMAN DENN domain-containing protein 4B OS=Homo sapiens GN=DENND4B PE=1 SV=4 (Range: 451-750)
HGM_OVER 18-74 -3.800 PB037276 Q24TM0_DESHY/1-190 PB037276; Pfam-B_37276;
JCSG0516 2-46 -5.570 20  MA16112A NP_083023.1 400173 Cloned-2009-02-26
NEW_HUMAN_DOMAINS 14-65 -6.360 27  sp|Q96RS6|NUDC1_HUMAN NudC domain-containing protein 1 OS=Homo sapiens GN=NUDCD1 PE=1 SV=2 (Range: 1-255)
PDB0516 3-75 -6.070 1yr6_A mol:protein length:262 ATP(GTP)binding protein
PfamA30U 3-75 -7.300 14  PF03029.15; O01426_CAEEL/6-251; Conserved hypothetical ATP binding protein
SCOP206 3-75 -5.870 d1yrba2 c.37.1.10 (A:1-245) ATP(GTP)-binding protein PAB0955 {Pyrococcus abyssi [TaxId: 29292]}
VFDB 9-74 -4.230 18  VFG001944(gi:15792468) (neuA1) bifunctional beta-1,4-N-acetylgalactosaminyltransferase/CMP-Neu5Ac synthase [LOS (VF0326)] [Campylobacter jejuni subsp. jejuni NCTC 11168]
3 gi|6319250|ref|NP_009333.1| Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide; Seo1p (YAL067C) [Saccharomyces cerevisiae] 593 COG0516 57-585 -74.000 13  [G] KOG2533 Permease of the major facilitator superfamily
H.sapiens 42-576 -28.400 10  sp|Q8IVW8|SPNS2_HUMAN Protein spinster homolog 2 OS=Homo sapiens GN=SPNS2 PE=1 SV=2
79-593 -28.700 11  sp|Q9H2V7|SPNS1_HUMAN Protein spinster homolog 1 OS=Homo sapiens GN=SPNS1 PE=1 SV=1
96-577 -29.200 10  sp|Q9H3U5|MFSD1_HUMAN Major facilitator superfamily domain-containing protein 1 OS=Homo sapiens GN=MFSD1 PE=2 SV=2
129-565 -34.900 sp|O43826|G6PT1_HUMAN Glucose-6-phosphate translocase OS=Homo sapiens GN=SLC37A4 PE=1 SV=1
HGM_OVER 258-359 -4.420 12  PB006154 _JGI.0331794_ 2004021056 [Human Gut Community Subject 7]
JCSG0516 132-565 -29.900 10  TM1007 TM1007 354152 Purified-2001-10-30
NEW_HUMAN_DOMAINS 192-342 -5.560 16  tr|C9J3Y5|C9J3Y5_HUMAN Uncharacterized protein OS=Homo sapiens GN=FAM72D PE=4 SV=1 (Range: 1-149)
PDB0516 125-568 -32.600 12  1pw4_A mol:protein length:451 Glycerol-3-phosphate transporter
PfamA30U 96-593 -11.300 PF06609.11; Q8NII4_FUSAU/1-598; Fungal trichothecene efflux pump (TRI12)
143-514 -16.200 10  PF07690.14; Q9KBG2_BACHD/16-398; Major Facilitator Superfamily
159-552 -15.400 10  PF06779.12; Q8Y185_RALSO/36-399; Uncharacterised MFS-type transporter YbfB
SCOP206 125-564 -32.600 12  d1pw4a1 f.38.1.1 (A:5-448) Glycerol-3-phosphate transporter {Escherichia coli [TaxId: 562]}
VFDB 125-565 -33.300 12  VFG001089(gi:16802879) (hpt) hexose phosphate transport protein [Hpt (VF0264)] [Listeria monocytogenes EGD-e]
4 gi|6319252|ref|NP_009335.1| Putative protein of unknown function; has homology to FLO1; possible pseudogene; (YAL065C) [Saccharomyces cerevisiae] 128 COG0516 79-128 -7.120 26  [T] KOG3797 Peripheral-type benzodiazepine receptor and related proteins
H.sapiens 116-128 -7.430 15  sp|Q70CQ2|UBP34_HUMAN Ubiquitin carboxyl-terminal hydrolase 34 OS=Homo sapiens GN=USP34 PE=1 SV=2 (Range: 451-750)
HGM_OVER 99-122 -4.560 12  HGC00690 gi|162868815|dbj|BABB01001192.1|3.0 TMP00870;
JCSG0516 112-127 -7.270 31  SP18376A NP_372096.1 413708 Purified-2010-11-20
NEW_HUMAN_DOMAINS 82-118 -6.160 sp|Q8NHR7|CO043_HUMAN Uncharacterized protein C15orf43 OS=Homo sapiens GN=C15orf43 PE=2 SV=1 (Range: 154-220)
PDB0516 18-113 -7.890 25  4wse_A mol:protein length:584 Putative poly(A) polymerase catalytic subunit
PfamA30U 72-127 -6.560 20  PF15706.3; W5Q6M8_SHEEP/854-937; Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
SCOP206 68-124 -6.440 24  d1h6va2 c.3.1.5 (A:171-292) Mammalian thioredoxin reductase {Norway rat (Rattus norvegicus) [TaxId: 10116]}
VFDB 69-127 -6.330 16  VFG000138(gi:15598350) (wzy) O-antigen chain length regulator [LPS (VF0085)] [Pseudomonas aeruginosa PAO1]
5 gi|6319253|ref|NP_009336.1| Fungal-specific protein of unknown function; Yal064w-bp (YAL064W-B) [Saccharomyces cerevisiae] 126 COG0516 1-114 -7.190 10  [I] KOG3750 Inositol phospholipid synthesis protein, Scs3p
H.sapiens 35-114 -8.110 15  sp|O94886|TM63A_HUMAN Transmembrane protein 63A OS=Homo sapiens GN=TMEM63A PE=1 SV=3 (Range: 601-807)
HGM_OVER 60-126 -3.870 15  PB001404 Q2S5L8_SALRD/1-256 PB001404; Pfam-B_1404;
JCSG0516 69-119 -5.940 23  SP19381A YP_002937011.1 411144 Purified-2010-09-29
NEW_HUMAN_DOMAINS 5-113 -5.970 24  sp|Q96AG3|S2546_HUMAN Solute carrier family 25 member 46 OS=Homo sapiens GN=SLC25A46 PE=1 SV=1 (Range: 171-293)
PDB0516 13-52 -5.740 22  3tsi_A mol:protein length:65 Hemagglutinin-neuraminidase
PfamA30U 26-103 -6.260 18  PF11947.6; K9VCC6_9CYAN/5-154; Protein of unknown function (DUF3464 topsan)
SCOP206 45-124 -4.970 12  d1loua_ d.58.14.1 (A:) Ribosomal protein S6 {Thermus thermophilus [TaxId: 274]}
VFDB 25-88 -6.360 20  VFG037136(gi:15677705) (fHbp) factor H binding protein [fHbp (VF0452)] [Neisseria meningitidis MC58]
6 gi|7839146|ref|NP_058136.1| Putative protein of unknown function; YAL064C-A is not an essential gene; Yal064c-ap (YAL064C-A) [Saccharomyces cerevisiae] 126 COG0516 6-110 -7.590 [S] COG4719 Uncharacterized protein conserved in bacteria
H.sapiens 1-112 -40.600 12  sp|P08F94|PKHD1_HUMAN(removed signalp:1-23) Fibrocystin OS=Homo sapiens GN=PKHD1 PE=1 SV=1 (Range: 301-600)
HGM_OVER 8-94 -4.700 PB017610 Q11T14_CYTH3/22-188 PB017610; Pfam-B_17610;
JCSG0516 1-106 -11.700 SP17392A ZP_03460696.1 407633 Purified-2010-09-29
NEW_HUMAN_DOMAINS 2-111 -8.310 10  sp|A4D0S4|LAMB4_HUMAN Laminin subunit beta-4 OS=Homo sapiens GN=LAMB4 PE=2 SV=1 (Range: 585-721)
PDB0516 1-124 -54.800 71  4gq7_A mol:protein length:224 Flocculin
PfamA30U 1-117 -49.800 14  PF10528.7; YQ39_SCHPO/481-593; GLEYA domain
SCOP206 1-125 -53.500 80  d2xjpa1 b.179.1.2 (A:23-271) GLEYA domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
VFDB 2-123 -27.200 12  VFG002295(gi:3478672) (C2II) C2 toxin (component-II) [C2 toxin (VF0384)] [Clostridium botulinum C str. 203U28]
7 gi|6319254|ref|NP_009337.1| Protein of unknown function; may interact with ribosomes, based on co-purification experiments; (YAL064W) [Saccharomyces cerevisiae] 108 COG0516 1-81 -7.320 22  [S] COG4642 Uncharacterized protein conserved in bacteria
H.sapiens 12-107 -7.010 19  sp|Q5THJ4|VP13D_HUMAN Vacuolar protein sorting-associated protein 13D OS=Homo sapiens GN=VPS13D PE=1 SV=1 (Range: 1951-2250)
HGM_OVER 14-73 -4.040 16  PB045813 Q5LF03_BACFN/1-275 PB045813; Pfam-B_45813;
JCSG0516 1-108 -6.400 22  RH11939G NP_436994.1 416317 Selected-2009-12-04
NEW_HUMAN_DOMAINS 11-96 -6.180 17  sp|Q9Y597|KCTD3_HUMAN BTB/POZ domain-containing protein KCTD3 OS=Homo sapiens GN=KCTD3 PE=1 SV=2 (Range: 179-413)
PDB0516 4-102 -7.700 2e1m_B mol:protein length:130 L-glutamate oxidase
PfamA30U 15-82 -7.100 16  PF01822.17; A7ERH4_SCLS1/37-114; WSC domain
SCOP206 49-94 -6.370 23  d1nuba3 g.68.1.1 (A:78-135) Domain of BM-40/SPARC/osteonectin {Human (Homo sapiens) [TaxId: 9606]}
VFDB 13-98 -5.000 20  VFG000007(gi:33592928) (fimB) chaperone protein [Fimbriae (VF0031)] [Bordetella pertussis Tohama I]
8 gi|33438755|ref|NP_878039.1| Putative protein of unknown function; identified by expression profiling and mass spectrometry; Yal063c-ap (YAL063C-A) [Saccharomyces cerevisiae] 96 COG0516 16-96 -5.600 19  [K] COG5414 TATA-binding protein-associated factor
H.sapiens 37-82 -7.320 19  sp|Q96IM9|DYDC2_HUMAN DPY30 domain-containing protein 2 OS=Homo sapiens GN=DYDC2 PE=1 SV=1
HGM_OVER 7-83 -5.650 15  PB002776 gi|157737147|ref|YP_001489830.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]gi|157699001|gb|ABV67161.1| hypothetical protein Abu_0901 [Arcobacter butzleri RM4018]
JCSG0516 26-95 -6.440 24  SP19163A YP_909014.1 409986 Purified-2010-09-29
NEW_HUMAN_DOMAINS 28-95 -8.630 17  sp|Q9Y2B1|TMEM5_HUMAN Transmembrane protein 5 OS=Homo sapiens GN=TMEM5 PE=2 SV=1 (Range: 354-443)
PDB0516 3-86 -7.290 16  2cq1_A mol:protein length:101 PTB-like protein L
PfamA30U 31-91 -6.620 26  PF13798.4; X2GN24_9BACI/8-168; Protein of unknown function with PCYCGC motif
SCOP206 5-96 -6.580 22  d1tbfa_ a.211.1.2 (A:) cGMP-specific 3`,5`-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
VFDB 15-96 -5.600 15  VFG001856(gi:52841094) (ccmC) cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [CcmC (VF0292)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
9 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] (Range: 1-500) 500 COG0516 144-500 -11.900 [R] KOG3253 Predicted alpha/beta hydrolase
182-500 -19.400 10  [S] KOG4502 Predicted membrane protein
199-487 -22.300 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
H.sapiens 5-353 -19.100 sp|Q86WI1|PKHL1_HUMAN(removed signalp:1-20) Fibrocystin-L OS=Homo sapiens GN=PKHD1L1 PE=2 SV=2 (Range: 301-600)
6-299 -19.700 12  sp|P08F94|PKHD1_HUMAN(removed signalp:1-23) Fibrocystin OS=Homo sapiens GN=PKHD1 PE=1 SV=1 (Range: 301-600)
344-499 -22.100 12  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
HGM_OVER 3-144 -3.530 11  PB009233 Q7MX23_PORGI/1-175 PB009233; Pfam-B_9233;
JCSG0516 5-499 -14.000 RF20619A.CABIN1 BC054497 421217 Purified-2010-12-07
165-500 -16.900 14  SP2600M ZP_02027330.1 411361 Selected-2009-11-12
245-500 -21.100 RF20622A.ZCCHC8 BC065918 421231 Purified-2010-12-01
NEW_HUMAN_DOMAINS 111-500 -7.550 sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2 (Range: 471-1300)
PDB0516 1-249 -56.700 87  4lhl_A mol:protein length:263 Flocculation protein FLO1
6-500 -16.500 4ee2_A mol:protein length:736 Protective antigen
PfamA30U 12-216 -16.300 11  PF07691.10; Q7SG54_NEUCR/449-597; PA14 domain
113-229 -28.700 18  PF10528.7; YQ39_SCHPO/481-593; GLEYA domain
188-499 -15.300 PF15741.3; U3I1Q0_ANAPL/22-754; Ligand-dependent nuclear receptor-interacting factor 1
SCOP206 1-245 -56.000 89  d2xjpa1 b.179.1.2 (A:23-271) GLEYA domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
VFDB 6-499 -15.600 VFG000677(gi:4894326) (pagA) anthrax toxin moiety, protective antigen [Anthrax toxin (VF0142)] [Bacillus anthracis str. Sterne]
10 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] (Range: 251-750) 500 COG0516 1-478 -15.200 [TU] KOG3895 Synaptic vesicle protein Synapsin
14-316 -21.500 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
H.sapiens 1-161 -18.900 sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
10-485 -10.100 sp|Q86Y22|CONA1_HUMAN Collagen alpha-1(XXIII) chain OS=Homo sapiens GN=COL23A1 PE=1 SV=1
84-210 -13.500 sp|P49750|YLPM1_HUMAN YLP motif-containing protein 1 OS=Homo sapiens GN=YLPM1 PE=1 SV=3 (Range: 1051-1350)
197-302 -12.100 10  sp|Q4G0P3|HYDIN_HUMAN Hydrocephalus-inducing protein homolog OS=Homo sapiens GN=HYDIN PE=1 SV=2 (Range: 2101-2400)
197-394 -10.300 sp|Q86VR2|F134C_HUMAN Protein FAM134C OS=Homo sapiens GN=FAM134C PE=1 SV=1
HGM_OVER 10-89 -1.240 PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
JCSG0516 1-169 -16.500 14  SP2600AD YP_794564.1 411897 Selected-2009-11-12
1-251 -16.100 RF20622A.ZCCHC8 BC065918 421231 Purified-2010-12-01
267-439 -14.000 11  SP2363I ZP_03458730.1 407556 Purified-2010-09-29
319-500 -14.900 11  SP2363E ZP_02069969.1 409482 Purified-2010-09-29
NEW_HUMAN_DOMAINS 2-456 -3.710 sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2 (Range: 471-1300)
PDB0516 17-498 -13.300 3hqv_A mol:protein length:1056 Collagen alpha-1(I) chain
PfamA30U 1-412 -12.000 PF17076.3; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP206 1-96 -2.520 14  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 14-296 -11.900 VFG002419(gi:21281935) (coa) staphylocoagulase precursor [Staphylocoagulase (VF0421)] [Staphylococcus aureus subsp. aureus MW2]
15-449 -10.600 11  VFG000337(gi:16272928) (iga1) immunoglobin A1 protease [IgA1 protease (VF0045)] [Haemophilus influenzae Rd KW20]
11 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] (Range: 501-1000) 500 COG0516 1-298 -22.100 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
1-500 -16.300 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
H.sapiens 1-161 -20.000 13  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
15-263 -12.800 sp|O15240|VGF_HUMAN(removed signalp:1-22) Neurosecretory protein VGF OS=Homo sapiens GN=VGF PE=1 SV=2
404-500 -11.500 13  sp|Q5T200|ZC3HD_HUMAN Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens GN=ZC3H13 PE=1 SV=1 (Range: 1051-1350)
HGM_OVER 1-81 -2.430 PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
JCSG0516 1-173 -17.500 SP2600AD YP_794564.1 411897 Selected-2009-11-12
1-252 -17.400 RF20622A.ZCCHC8 BC065918 421231 Purified-2010-12-01
13-423 -14.500 RF20619A.CABIN1 BC054497 421217 Purified-2010-12-07
300-500 -15.500 15  SP2363O YP_001299585.1 409884 Selected-2009-11-12
336-500 -15.800 13  SP2363A YP_211281.1 407957 Purified-2010-09-29
NEW_HUMAN_DOMAINS 1-432 -2.810 sp|A6NHR9|SMHD1_HUMAN Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens GN=SMCHD1 PE=1 SV=2 (Range: 471-1300)
PDB0516 1-144 -11.600 13  5i4d_A mol:protein length:343 Superantigen-like protein
14-251 -9.920 10  4cwu_T mol:protein length:368 CORE-CAPSID BRIDGING PROTEIN
PfamA30U 1-276 -12.300 10  PF08549.8; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)
6-427 -11.900 10  PF17076.3; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP206 1-97 -2.280 13  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-424 -13.100 11  VFG000337(gi:16272928) (iga1) immunoglobin A1 protease [IgA1 protease (VF0045)] [Haemophilus influenzae Rd KW20]
12 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] (Range: 751-1250) 500 COG0516 1-467 -16.500 10  [TU] KOG3895 Synaptic vesicle protein Synapsin
197-500 -23.500 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
H.sapiens 1-161 -20.500 13  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
1-201 -13.000 sp|Q86VR2|F134C_HUMAN Protein FAM134C OS=Homo sapiens GN=FAM134C PE=1 SV=1
1-270 -11.800 sp|Q8NC44|F134A_HUMAN Protein FAM134A OS=Homo sapiens GN=FAM134A PE=1 SV=3
1-315 -9.840 15  sp|Q9NXV6|CARF_HUMAN CDKN2A-interacting protein OS=Homo sapiens GN=CDKN2AIP PE=1 SV=2
303-500 -11.400 sp|O15240|VGF_HUMAN(removed signalp:1-22) Neurosecretory protein VGF OS=Homo sapiens GN=VGF PE=1 SV=2
361-490 -14.300 sp|P49750|YLPM1_HUMAN YLP motif-containing protein 1 OS=Homo sapiens GN=YLPM1 PE=1 SV=3 (Range: 1051-1350)
403-500 -18.100 sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containing protein 1A OS=Homo sapiens GN=ARID1A PE=1 SV=3 (Range: 451-750)
HGM_OVER 10-86 -2.070 PB069407 _HOMD.0084606_ pint_c_2_12 Prevotella intermedia 17 [3585 - 4295] ORF
JCSG0516 1-172 -19.200 11  SP2600AD YP_794564.1 411897 Selected-2009-11-12
1-250 -17.600 RF20622A.ZCCHC8 BC065918 421231 Purified-2010-12-01
34-462 -15.100 10  SP17586C NP_439153.1 411588 Selected-2009-11-12
305-500 -16.900 SP2363O YP_001299585.1 409884 Selected-2009-11-12
NEW_HUMAN_DOMAINS 466-499 -4.040 20  sp|P18583|SON_HUMAN Protein SON OS=Homo sapiens GN=SON PE=1 SV=4 (Range: 606-751)
PDB0516 1-147 -11.800 5i4d_A mol:protein length:343 Superantigen-like protein
1-212 -9.670 11  5fur_J mol:protein length:677 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT
PfamA30U 1-265 -12.900 PF08549.8; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)
98-500 -11.900 11  PF17076.3; SBE22_CANGA/1-813; SBE2, cell-wall formation
SCOP206 54-155 -2.080 10  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-246 -10.200 VFG004773(gi:21284319) (lip) triacylglycerol lipase precursor [Lipase (CVF091)] [Staphylococcus aureus subsp. aureus MW2]
34-462 -15.100 10  VFG000337(gi:16272928) (iga1) immunoglobin A1 protease [IgA1 protease (VF0045)] [Haemophilus influenzae Rd KW20]
229-500 -12.100 VFG002419(gi:21281935) (coa) staphylocoagulase precursor [Staphylocoagulase (VF0421)] [Staphylococcus aureus subsp. aureus MW2]
13 gi|6319255|ref|NP_009338.1|(removed signalp:1-24) Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation; Flo9p (YAL063C) [Saccharomyces cerevisiae] (Range: 1001-1298) 298 COG0516 2-287 -26.100 [R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)
H.sapiens 2-162 -21.900 10  sp|Q9H3R2|MUC13_HUMAN(removed signalp:1-18) Mucin-13 OS=Homo sapiens GN=MUC13 PE=1 SV=2
10-285 -13.700 sp|Q8NC44|F134A_HUMAN Protein FAM134A OS=Homo sapiens GN=FAM134A PE=1 SV=3
74-239 -18.400 sp|P49750|YLPM1_HUMAN YLP motif-containing protein 1 OS=Homo sapiens GN=YLPM1 PE=1 SV=3 (Range: 601-900)
HGM_OVER 229-298 -3.180 PB030138 Q7MX14_PORGI/1-113 PB030138; Pfam-B_30138;
JCSG0516 1-279 -16.900 16  SP2600M ZP_02027330.1 411361 Selected-2009-11-12
10-256 -20.200 RF20622A.ZCCHC8 BC065918 421231 Purified-2010-12-01
NEW_HUMAN_DOMAINS 1-47 -3.100 12  sp|Q92750|TAF4B_HUMAN Transcription initiation factor TFIID subunit 4B OS=Homo sapiens GN=TAF4B PE=1 SV=2 (Range: 450-595)
PDB0516 1-147 -14.400 5i4d_A mol:protein length:343 Superantigen-like protein
2-236 -12.100 10  5fur_J mol:protein length:677 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT
58-298 -10.900 4cwu_T mol:protein length:368 CORE-CAPSID BRIDGING PROTEIN
PfamA30U 2-287 -15.600 PF08549.8; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)
SCOP206 2-102 -2.720 10  d3c0na2 f.8.1.1 (A:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
VFDB 1-271 -14.300 VFG002419(gi:21281935) (coa) staphylocoagulase precursor [Staphylocoagulase (VF0421)] [Staphylococcus aureus subsp. aureus MW2]
14 gi|6319256|ref|NP_009339.1| NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; Gdh3p (YAL062W) [Saccharomyces cerevisiae] 457 COG0516 3-457 -52.000 24  [E] KOG2250 Glutamate/leucine/phenylalanine/valine dehydrogenases
31-454 -60.800 28  [E] COG0334 Glutamate dehydrogenase/leucine dehydrogenase
H.sapiens 3-457 -52.500 24  sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens GN=GLUD1 PE=1 SV=2
HGM_OVER 1-128 -2.950 PB007733 A3U921_9FLAO/1-209 PB007733; Pfam-B_7733;
JCSG0516 30-447 -62.900 19  FL11458A YP_009599.1 375534 Crystal|NMR-2007-06-28
NEW_HUMAN_DOMAINS 4-100 -5.570 12  sp|Q96MP5|ZSWM3_HUMAN Zinc finger SWIM domain-containing protein 3 OS=Homo sapiens GN=ZSWIM3 PE=1 SV=2 (Range: 321-428)
PDB0516 2-457 -131.000 48  1aup_A mol:protein length:449 NAD-SPECIFIC GLUTAMATE DEHYDROGENASE
PfamA30U 40-168 -47.500 31  PF02812.16; R6WCN3_9CLOT/34-162; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
185-454 -40.900 32  PF00208.19; Q6H3Y7_ORYSJ/176-408; Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
SCOP206 2-179 -94.800 59  d1bgva2 c.58.1.1 (A:1-194) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}
180-457 -89.400 42  d1bgva1 c.2.1.7 (A:195-449) Glutamate dehydrogenase {Clostridium symbiosum [TaxId: 1512]}
VFDB 5-454 -6.440 12  VFG015515(gi:15599409) (phzE1) phenazine biosynthesis protein PhzE [Phenazines biosynthesis (CVF536)] [Pseudomonas aeruginosa PAO1]
15 gi|6319257|ref|NP_009340.1| Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene; Bdh2p (YAL061W) [Saccharomyces cerevisiae] 417 COG0516 1-382 -78.200 29  [Q] KOG0024 Sorbitol dehydrogenase
H.sapiens 1-382 -77.900 29  sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=SORD PE=1 SV=4
1-415 -32.800 19  sp|Q9HCJ6|VAT1L_HUMAN Synaptic vesicle membrane protein VAT-1 homolog-like OS=Homo sapiens GN=VAT1L PE=1 SV=2
HGM_OVER 197-288 -3.920 15  HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;
JCSG0516 1-375 -79.100 24  MH15431A YP_001166108.1 394306 Crystal|NMR-2009-06-23
NEW_HUMAN_DOMAINS 172-247 -6.110 18  sp|Q9UPA5|BSN_HUMAN Protein bassoon OS=Homo sapiens GN=BSN PE=1 SV=4 (Range: 1710-1779)
PDB0516 1-376 -84.600 24  4a2c_A mol:protein length:346 GALACTITOL-1-PHOSPHATE 5-DEHYDROGENASE
1-415 -36.500 17  4a0s_A mol:protein length:447 OCTENOYL-COA REDUCTASE/CARBOXYLASE
PfamA30U 26-159 -37.900 36  PF08240.10; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
167-387 -40.900 16  PF16912.3; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
SCOP206 1-203 -64.700 29  d1pl8a1 b.35.1.2 (A:1-145,A:317-356) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
164-337 -48.700 26  d1pl8a2 c.2.1.1 (A:146-316) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 175-291 -6.930 11  VFG010898(gi:52840984) (iraA) Small-molecule methyltransferase IraA [Iron acquisition/assimilation locus (CVF361)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
16 gi|6319258|ref|NP_009341.1| NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source; Bdh1p (YAL060W) [Saccharomyces cerevisiae] 382 COG0516 2-380 -79.500 26  [Q] KOG0024 Sorbitol dehydrogenase
H.sapiens 1-380 -79.200 25  sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo sapiens GN=SORD PE=1 SV=4
HGM_OVER 197-292 -4.380 18  HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;
JCSG0516 1-374 -79.200 23  MH15431A YP_001166108.1 394306 Crystal|NMR-2009-06-23
NEW_HUMAN_DOMAINS 78-136 -5.400 13  sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1 SV=5 (Range: 553-630)
PDB0516 1-375 -85.000 22  4a2c_A mol:protein length:346 GALACTITOL-1-PHOSPHATE 5-DEHYDROGENASE
PfamA30U 26-159 -37.900 32  PF08240.10; A9CHB7_AGRFC/24-130; Alcohol dehydrogenase GroES-like domain
167-382 -43.000 19  PF16912.3; I7BJ28_NATSJ/144-370; Glucose dehydrogenase C-terminus
SCOP206 1-203 -64.900 25  d1pl8a1 b.35.1.2 (A:1-145,A:317-356) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
164-336 -48.900 24  d1pl8a2 c.2.1.1 (A:146-316) Ketose reductase (sorbitol dehydrogenase) {Human (Homo sapiens) [TaxId: 9606]}
VFDB 175-290 -7.340 13  VFG010898(gi:52840984) (iraA) Small-molecule methyltransferase IraA [Iron acquisition/assimilation locus (CVF361)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
17 gi|6319259|ref|NP_009342.1| Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export; Ecm1p (YAL059W) [Saccharomyces cerevisiae] 212 COG0516 3-154 -6.290 11  [R] KOG0151 Predicted splicing regulator, contains RRM, SWAP and RPR domains
H.sapiens 16-145 -9.280 sp|Q9UBU6|FA8A1_HUMAN Protein FAM8A1 OS=Homo sapiens GN=FAM8A1 PE=1 SV=1
HGM_OVER 2-130 -4.780 10  PB202086 Q8G498_BIFLO/2-200 PB202086; Pfam-B_202086;
JCSG0516 1-209 -10.800 SP18938A YP_808885.1 412031 Selected-2009-11-12
NEW_HUMAN_DOMAINS 2-51 -7.710 18  sp|Q8IX21|F178A_HUMAN Protein FAM178A OS=Homo sapiens GN=FAM178A PE=1 SV=2 (Range: 908-1046)
PDB0516 18-145 -6.960 10  4h63_Q mol:protein length:469 Mediator of RNA polymerase II transcription s
PfamA30U 31-152 -58.000 52  PF09135.9; Q6CLT8_KLULA/8-125; Alb1
SCOP206 9-183 -8.060 d3rlff1 e.70.1.1 (F:10-260) Maltose transport system permease protein MalF {Escherichia coli [TaxId: 562]}
VFDB 2-212 -7.210 VFG004773(gi:21284319) (lip) triacylglycerol lipase precursor [Lipase (CVF091)] [Staphylococcus aureus subsp. aureus MW2]
18 gi|6319260|ref|NP_009343.1|(removed signalp:1-19) Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast; Cne1p (YAL058W) [Saccharomyces cerevisiae] 483 COG0516 1-482 -111.000 27  [O] KOG0675 Calnexin
H.sapiens 1-482 -113.000 29  sp|P27824|CALX_HUMAN(removed signalp:1-20) Calnexin OS=Homo sapiens GN=CANX PE=1 SV=2
HGM_OVER 153-264 -3.090 HGC00965 gi|163282470|dbj|BABD01028218.1|2.0 TMP01310;
JCSG0516 12-227 -68.300 25  KN.B21266A.CALR BC007911 429601 Purified-2014-04-01
NEW_HUMAN_DOMAINS 293-406 -40.900 15  sp|Q99932|SPAG8_HUMAN Sperm-associated antigen 8 OS=Homo sapiens GN=SPAG8 PE=1 SV=2 (Range: 202-321)
PDB0516 1-420 -115.000 31  1jhn_A mol:protein length:424 calnexin
PfamA30U 14-394 -110.000 32  PF00262.16; R4XC34_TAPDE/40-408; Calreticulin family
SCOP206 3-261 -54.900 23  d1jhna4 b.29.1.12 (A:61-262,A:412-458) Calnexin {Dog (Canis familiaris) [TaxId: 9615]}
222-363 -83.700 44  d1jhna3 b.104.1.1 (A:270-411) Calnexin {Dog (Canis familiaris) [TaxId: 9615]}
VFDB 63-409 -5.150 VFG013365(gi:16272813) (wbaP/rfbP) undecaprenyl-phosphate galactosephosphotransferase [LOS (CVF494)] [Haemophilus influenzae Rd KW20]
19 gi|41629666|ref|NP_009345.2| Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p; Gpb2p (YAL056W) [Saccharomyces cerevisiae] 880 COG0516 4-765 -28.300 [TR] KOG4441 Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
156-870 -54.000 [T] KOG2437 Muskelin
265-874 -57.500 11  [R] KOG0379 Kelch repeat-containing proteins
H.sapiens 6-768 -28.800 sp|Q0D2K2|KLH30_HUMAN Kelch-like protein 30 OS=Homo sapiens GN=KLHL30 PE=2 SV=2
271-759 -59.600 13  sp|Q8N653|LZTR1_HUMAN Leucine-zipper-like transcriptional regulator 1 OS=Homo sapiens GN=LZTR1 PE=2 SV=2 (Range: 1-300)
340-867 -57.800 12  sp|Q7Z6M1|RABEK_HUMAN Rab9 effector protein with kelch motifs OS=Homo sapiens GN=RABEPK PE=1 SV=1
HGM_OVER 1-540 -5.670 PB048631 gi|160885545|ref|ZP_02066548.1| hypothetical protein BACOVA_03545 [Bacteroides ovatus ATCC 8483]gi|156109167|gb|EDO10912.1| hypothetical protein BACOVA_03545 [Bacteroides ovatus ATCC 8483]
JCSG0516 4-863 -19.000 11  SP13647T ZP_01959481.1 406843 Selected-2009-11-12
248-867 -59.800 14  RV3356A XM_002722628 423301 Purified-2012-08-23
NEW_HUMAN_DOMAINS 45-124 -7.480 10  sp|Q86UP8|GTD2A_HUMAN General transcription factor II-I repeat domain-containing protein 2A OS=Homo sapiens GN=GTF2IRD2 PE=2 SV=2 (Range: 426-506)
PDB0516 1-760 -25.300 11  2zw9_A mol:protein length:695 Leucine carboxyl methyltransferase 2
258-778 -52.600 13  5a10_A mol:protein length:356 THIOCYANATE FORMING PROTEIN
356-865 -30.800 13  2uvk_A mol:protein length:357 YJHT
PfamA30U 691-751 -20.200 18  PF13415.4; D0NJE7_PHYIT/261-311; Galactose oxidase, central domain
SCOP206 201-760 -12.500 14  d1k3ia3 b.69.1.1 (A:151-537) Galactose oxidase, central domain {Fungus (Fusarium sp.) [TaxId: 29916]}
287-753 -26.600 d3ii7a_ b.68.11.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
288-807 -24.400 13  d1zgka1 b.68.11.1 (A:322-609) Kelch-like ECH-associated protein 1, KEAP1 {Human (Homo sapiens) [TaxId: 9606]}
VFDB 1-880 -8.790 11  VFG042861(gi:52840865) (pilY1) type IV pilus biogenesis PilY1-related protein [type IV pili (AI111)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
20 gi|6319263|ref|NP_009346.1| Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation; Pex22p (YAL055W) [Saccharomyces cerevisiae] 180 COG0516 5-131 -7.140 [S] COG5353 Uncharacterized protein conserved in bacteria
H.sapiens 56-167 -7.830 14  sp|Q96MI6|PPM1M_HUMAN Protein phosphatase 1M OS=Homo sapiens GN=PPM1M PE=2 SV=1
HGM_OVER 1-95 -4.820 12  HGC00672 gi|162843654|dbj|BABA01001055.1|4.0 TMP00845;
JCSG0516 1-168 -8.390 SP16379A ZP_04008557.1 413838 Purified-2010-09-29
NEW_HUMAN_DOMAINS 80-134 -7.120 14  sp|Q9H869|YYAP1_HUMAN YY1-associated protein 1 OS=Homo sapiens GN=YY1AP1 PE=1 SV=2 (Range: 269-383)
PDB0516 51-180 -74.500 97  2y9m_B mol:protein length:130 PEROXISOME ASSEMBLY PROTEIN 22
PfamA30U 51-167 -53.800 22  PF12827.5; C4Y073_CLAL4/43-162; Peroxisomal biogenesis protein family
SCOP206 40-180 -6.350 d1fo8a_ c.68.1.10 (A:) N-acetylglucosaminyltransferase I {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
VFDB 2-178 -6.460 VFG014486(gi:15596639) (fliL) flagellar basal body protein FliL [Deoxyhexose linking sugar, 209 Da capping structure (AI138)] [Pseudomonas aeruginosa PAO1]


FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Li W, Pio F, Pawlowski K, Godzik A. Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology. Bioinformatics. 2000 Dec;16(12):1105-10.