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anford Burnham Prebys Medical Discovery Institute
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Query: TM0013 TM0013 281894 Purified-2001-08-24, from JCSG0516

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFENEILFDNGQHKFMFLGWEEKEEEIVQTNQYLILDGNEGILLDPGGAHVFPRVMSNVAEVVDLSSIRHIFYTHQDPDVTSGILLWLSICENAKIYISSLWVRFLPHFGIYDQKRIVPISDKGTKIKLLSGNELEILPAHFLHSTGNFVLYDPVAKILFSGDIGAAVFEKGKRYRYVDDFERHLPLMEAFHKRYMSSNAACKKWVDMVSKKKIDMIAPQHGAVFRGESVKKFLEWFRNLKCGVDLIDNLYSLLast
1 -5.790 VFG001232(gi:15595611) (chpB) probable methylesterase [Type IV pili (VF0082)] [Pseudomonas aeruginosa PAO1]  ali follow..  10  147....................................AAREVWLLSLGGPAAVKAFLDALPGGLP---IGFLYAQHIDASFEQNLPQAVGRHSQWHVKNVRDGEALRCG--------EVMVVPVLHELGFHHDGRLKCSQRSWPYTPSIDQMMLNLAQIVFSG--MGSDGSAAAAYVRRQGGEVWTQRADSCVCSSMPDSLREAGYSSFNASPR........................................ 322
2 -4.900 VFG002388(gi:15611017) (espB) ESX-1 type VII secretion system EspB [ESX-1 (VF0315)] [Mycobacterium tuberculosis H37Rv]  ali follow..  10  1...................................MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQ--ILHMAKLSAAM--AKQAQYVAQLHVWARREHPTYEDI... 229
3 -4.700 VFG002397(gi:15608920) (eccB5) ESX-5 type VII secretion system protein EccB5 [ESX-5 (VF0402)] [Mycobacterium tuberculosis H37Rv]  ali follow..  12  83.....................................NESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRS--SQIATMPRGPLVGIPGAPSSFSPKSPPASSWLVCDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQARPMSRALFDALPVGP-ELLVPE-GTVIVTPQISGPQQYSLVLGDGVQTLPPL... 308
4 -4.460 VFG000701(gi:30962649) (bsc2) polysaccharide biosynthesis protein Bsc2 [Capsule (VF0043)] [Haemophilus influenzae str. 1007]  ali follow..  10  67.......................................AYLDALKEGVIFYPFNAQSNCRAVANRNLTHIFITHGESNKITSVKPIVRIYDHVITAGNAGIDRLIAH--------------FSQYDVEAGRIIPMGD--TFIGKTGLDHTGKGIPAIFYVPTWEGGIEQEN------------------YSSLSYVGQVTNTLLLLSKHYQINEIVIRPHPNTGHRL......................... 223
5 -4.460 VFG034887(gi:15801293) (espX7/nleL) Type III secretion system effector NleL, putative E3 ubiquitin ligase [LEE encoded T3SS (SS020)] [Escherichia coli O157:H7 str. EDL933]  ali follow..  10  426.......................PNTSTNWMSFFLYKDGEVQ-----------NTFGYSLSNLFSESFPIFSIPYHKAFSQNFVSGIL----DILISDNELKERFIEALNSNKSDYKMIADDQQRKLACVWNPFLDGWELNAQHVDMIMGSHVKQAEILFCLGGVFCKYSSSDMFGTEYDSP---EILRRYANGL----------IEQAYKTDPQVF----SVYYYNDILDRLQGRNNVFTCTAVLTDML... 628
6 -4.440 VFG001936(gi:15792460) (Cj1135) glucosyltransferase [LOS (VF0326)] [Campylobacter jejuni subsp. jejuni NCTC 11168]  ali follow..  11  12....................VKNAKQTLLECLNSLKDFDEIILLNNESSDNTLNIANEFKKDFANLHIDWILSIDADNECIKELKNLKNLYKGEWIKACGWWPDYVWRIFNKNFTR-FNDNLVHESLVLPSNAKKIYLKNGLRHY-----AFRDISHLIDKMQYYSSLWAKQNIHKKSGVLKANLRAFWTFFRNYF-FKYMKLYELQKQKPKTCALIITTYNQKERLKLVLDSVKNLAFLPNEVLIADD.... 293
7 -4.410 VFG000131(gi:15598745) (algJ) alginate o-acetyltransferase AlgJ [Alginate (VF0091)] [Pseudomonas aeruginosa PAO1]  ali follow..  87...........................IGKDGWLFTDEEFKPAPSGQQLEDNWALVRGVQRELNRRGVKLVLA--VIPAKARLYPEHI-----GREQPAALHDSLYQDFLARARAAGIDSPDLLGSLRQAKDNGAVFLRTDT-HWSGAETVAQRLGAEIHKGDLLSFLPLDPDELLPRPEQLQQRTTEAAPALPGGQQSGAGDDLFGDSQQPRLALVGTSYSANPRWNFEGALKQALSA.............. 316
8 -4.300 VFG002383(gi:15611007) (eccCb1) ESX-1 type VII secretion system FtsK/SpoIIIE family protein EccCb1 [ESX-1 (VF0315)] [Mycobacterium tuberculosis H37Rv]  ali follow..  366..................................MHTNPHLLIFKSGKTTIAHAIARAICARNSPQQVRFMLA-----DYRSGLLDAVPDTHLLGAGAINRNSASLDEA----VQALAVNLKKRLPPTDLTTAQLR--SRSWWSGFDVVLLVDDWHMIVGAAGGMPPMAPLAPLLPAAADIGLHIIVTC---QMSQAYKATMDKFVGAAFGSGAPTMFPGQAFLVSPDGKEVI.................... 572
9 -4.070 VFG013412(gi:16273070) (lpxC) UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase [LOS (CVF494)] [Haemophilus influenzae Rd KW20]  ali follow..  13  34...........NTGVVYYRTDLNPAVAFPADPNSVRDTMLCTALINEQGVRISTV-EHLNAALAGLGIDNIIIEVDAPEI-GSASPFIYLLLDAGIEEQNAAKKFIR------IKQYVRVEDGDKWAEFKPYNGFRLFTIDFDH--PAIGKDVRNYEMNFSAQAFVHQISRARTFGFMKDIE-----------YLQSQGLVLGGSLDNAIVLDDYRILNEDGLRFKDELVRKMLDAIGDLYAGYNIIGDFKA. 260
10 -4.060 VFG012501(gi:26247125) (iroE) esterase [Salmochelin (IA013)] [Escherichia coli CFT073]  ali follow..  12  79............................PASGYPIL-----YMLD--GNAVMDRLDDELLKQLSEKTPPVIVVGYQTNLPFDLNSRAYDYTPAAE---SNNFRQLLETRIAPKVEQGLNIDRQRRGL--WGHSYGGLFVLDSWLSSSYFRSYYSASPSLGRGY--DALLSRVTAVEPLQFCTKHLTQGDNRETHAVGVLSKIHTTLTILKDKGVNA---GHGPMFNASFRQALLDISGENANYTAGCHEL... 316

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.