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Query: 1znb_A mol:protein length:232 METALLO-BETA-LACTAMASE, from PDB0516

Results of FFAS03 search in JCSG0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst AQKSVKISDDISITQLSDKVYTYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTETLVNWVADSLHAKVTTFIPNHWHGDCIGGLGYLQKKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTSKPLast
1 -71.000FL10934A YP_165938.1 375728 Purified-2007-06-12  ali follow..  19  6ASQGDMSEKKISFTEVGEGLYAFTAEGD--------PNSGVIIGDDSVMVVEAQATPRLAQKVIDCIREVTDKPISHVVLTHYHAVRVLGASAFG--AGQVIMSDTARSMVVERGLTWPTTTFSDSMTVYLGKRRVDIMHLGRAHTAGDAVIHVPDQNVMFTGDIVEYHSACYCG---DGHFNDWGNTLDNIAWF--DVDAIAPGRGDALVNAAIENTRDFVQSTYRPAAR. 249
2 -69.600TM0681 TM0681 282551 Purified-2001-10-17  ali follow..  20  13LLENYTTRGEKMITNLSDRVFVIGTGTS--------ANSVLVCGKKFCVLFDSTLFPEKARKIKEFAAEILGKEIAVVFNTHYHPDHTFGNEVFDR----IISHSLTRKSLEEMDLKFPDETFSERENYRFGDIVVEAVHLG-GHTPDSSIFVLKNEKIVICGDLLTTGIHAEI--VTDSDLFGWIEALSEIEKI--RADYFVPGHGKVGTIEDVRNMKDYISKVLRFREG. 238
3 -41.900TM1295 TM1295 283159 Purified-2004-11-17  ali follow..  18  1.....MRKDEYRATLLEPNVWHIADYRG--------DSMYLVVGEEKALLVDTGMG---EGDLKGFVRSITEKPV-EVVLTHAHWDHIMQANQFEK----VYLNHRDFQIIELFKINVNFLNVKEGDRFDLGGRTLEVIEV-PGHTPGSIVLLDRENRLLFSGDSVGAGHT-WMHLPGCLPLREYLKSLKKLKET-DSFEKIYHGHLTGTQPDYLDDLIKAVEGVIDLRGEP 218
4 -39.500TM0607 TM0607 282480 Purified-2001-02-22  ali follow..  21  8....................................VNIGVVYTENAAVLVDSGLDESVPRKISRLL----QKPPLYLINTHSHADHCGGNAFLKKRSTRVFAPKMEKEIIENTVFPSAVDEVIEEGTITIESVDLEIVPL-SGHSTNQIGVAVD--GVLFCADAVFSEETLRKHRIFVINVEKFLETLDFLEKT--SYSYYVPSHGEVTREKNRKAVENIINAVLEITVNP 224
5 -33.500FJ9329A YP_323572.1 370290 PDB-2007-03-23  ali follow..  12  5...............HRPDLYSWSTFNPARN---IDFNGFAWIRPEGNILIDPV---ALSNHDWKHLESLGG--VVWIVLTN--SDHVRSAKEIADQYTKIAGPVAEKENFPIY----CDRWLSDGDELVPG---LKVMELQGSKTPGELALLLEE-TTLITGDLVRAYRAGGLEILPDEKLMNKQKVVASVRRLLEKVEAVLVGDGWSVFRDGRDRLKELVATL....... 199
6 -32.500C.KS20803A NP_372069.1 423895 Purified-2012-05-01  ali follow..  15  9................................GLVDTNTYFIENDKAVILIDPSGE---SEKIIKKLNQI-NKPLKAILLTHAHFDHIGAVDDIVDRDVPVYMHEAEFDFLKDPVKNGADKFKLNEGSTEIEGFKFNVLHT-PGHSPGSLTYVF--DEFAVVGDTLFNNGIGRTD-LYKGDYETLVDSIQDKIFELEGDLPLFPGHGPYTT..................... 195
7 -30.500TM0013 TM0013 281894 Purified-2001-08-24  ali follow..  13  3........ENEILFDNGQHKFMFLGWEEKEEEI-VQTNQYLILDGNEGILLDPGGAHVFPRVMSNVAEVVDLSSIRHIFYTHQDPDVTSGILLWLSENAKIYISSLWVRFLPHFGIYDQKRIVDKGTKIKLSGNELEILPAHFLHSTGNFVLYDPVAKILFSGDIGAAVFEKGKRYRYVDDFERHLPLMEAFHKRY-KIDMIAPQHGAVFRGESVKKFLEWFRNLKCGV... 244
8 -29.700FN0013A AFE_0842 378921 Purified-2007-09-27  ali follow..  15  1...............MSQLLYKCIAFTDLVEGEGIQANQFLIVNNGEGMLLDPGGNLTYKNLLAEMASYFLPAHLDYVFASHEDPDIVASANGWLLTDAKILIANEWTRFLPHFCSKGMTAIPAQGMRVNLAGQELFVVPAHYMHSVGNFQVYDPVSKILFSGDLGANLVSGHDAAKGQKVCRLWTNMARGM-----DIEWIVPQHGASKGRETVLAFLDWFEGLESGP... 247
9 -29.100MM3808A 13278494 354611 Purified-2003-08-14  ali follow..  19  7...........RIEQLSSRVVRVLG-CNPGPMTLQGTNTYLVGTGSRRILIDTPSVPEYISCLKQALVE-FDTAIQEILVTHWHSDHSGGIVDICKNINNDTTYCIKKLRRNPQREEQQFIYIENGDVVKTEGATLRVLYT-PGHTDDHMALLLEEENAIFSGDCILGEGTTIF-----EDLYDYMNSLNNLLKI--KANIIYPGHGPV-----IHNAEAKILEYISHRNN. 219
10 -28.700MA3808A NP_057111.1 399812 Purified-2009-03-14  ali follow..  19  7...........RVERLSNRVVRVLG-CNPGPMTLQGTNTYLVGTGPRRILIDTPAIPEYISCLKQALTE-FNTAIQEIVVTHWHRDHSGGIGDICKSYCIKKLPRNPQREEIIGNGEQQYVYLKDGDVIKTEGATLRVLYT-PGHTDDHMALLLEEENAIFSGDCILGEGTTVF-----EDLYDYMNSLKELLKI--KADIIYPGHGPV-----IHNAEAKIQQYISHRNI. 219
11 -27.100MA16092B NP_808546.1 400112 Cloned-2009-03-24  ali follow..  16  36QGAGDAVRADGTVTLVLPRGWASDSSRGLAPSADGGSKTALEEAVRGPILVDTGGPWAR-GALLEALATVAPEDVTLVVGTHGHSDHIGNLGLFPEAALLVSHDFCLPEGLYLPH----GLCETQPLILGSGLQVWAT----PGHGGQRDVSVVVEGTVVVAGDVFERLGDEDSWQALSEDPVAQQRSRERILSV---ADVVVPGHGA........................ 237
12 -26.600TM0894 TM0894 282763 PDB-2005-05-26  ali follow..  12  1..........MELKILVTGGNVFVP----GRLNAHFSTVVYLEHKDRRIIIDPGNLSS-MDELEEKFSELGISPITDVLFTHVHLDHIFNSVLF--ENATFYVHEVYKTKNYLSFGTIVGRIYSKVIS-SLFDEKVKVFHT-PWHAREHLSFLLDTENVLITGDITPNRL-----SYYDIIKGYGSVQVKNFLDRVGRIDLLVFPHD......................... 200
13 -26.400MA16092A NP_981942.1 400061 Selected-2008-12-22  ali follow..  19  32EGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEAARGHILVDTGGPWAR-EALLGALAGVAPGDVTLVVGTNGHSDHIGNLGLFPG------AALLVSHDFCLPGGRYLPHGLGEGQPLRLGP-GLEVWAT-PGHGGQRDVSVVVAGTTVVAGDVFERDGDEDSWQALSEDPAAQERSRKRVLVV---ADVVVPGHGP........................ 232
14 -25.200MA16095B NP_081173.1 400254 Purified-2009-05-08  ali follow..  16  9..................................LEDNYMYLIIEEHAVAID----VAVAERLLEIAGRE-GVSLTMVLSTHHHWDHTRGNAELAHILPGLAVLG------ADERICALTRRLEHGEGLQFGAIHVRCLLT-PGHTSGHMSYFLPDSPALFSGDALSVAG---CGWHLEDTAQQMYQSLAKTLGTLPPETKVFCGHSNLEFAQKVEPCNEHVQAKLSWAQE. 202
15 -24.500MA16095A NP_996995.1 400077 Purified-2009-03-13  ali follow..  16  9..................................LEDNYMYLVIEELAVAVD----VAVPKRLLEIVGRE-GVSLTAVLTTHHHWDHARGNPELARLGLAVLG--------ADERIFSLTRRLAHGEELRFGAIHVRCLLT-PGHTAGHMSYFLPDPPALFSGDALSVAG---CGSCLEGSAQQMYQSLAELGTL-PPETKVFCGHSNLEFAQKVEPCNDHVRAKLSWAKA. 201
16 -21.100XB5432A 10175883 358570 Crystal|NMR-2005-05-26  ali follow..  10  30...............VPKPLWSRKYPSNEKNQIELRTDPFLIQLDGQNILVESGIGNGRFTDLEDDLQSLTVADIDAVLMTHLHFDHASGLAKQKEENAVIYASAREWAEMREPNIRSRNTYWEQNWRPVEQQVVT--MIHTGGHSDGHSIIVIEHETFIHLADIMPTHAHQNVLWVLAYDDYPMDSIFAKQAFASEQEAWYLFYHDYKYRAIKWNDEGEIVA......... 274
17 -20.300TM0755 TM0755 282625 PDB-2004-09-21  ali follow..  16  6..........TERIFDDPEIYIRYFEAVWEIPEGISYNAYLVKLNGANVLIDGWKGNYAKEFIDALSKIVDPKEITHIIVNHTEPDHSGSLPATLKTDVEIIASNFGKRLLEGFYGIKDVTVVKDGEEREIGGKKFKFVMTPWLHWPDTMVTYL--DGILFSCDVGLPHVTKYIVTVIGHYKNYILEGAEKLSSL--KIKALLPGHGLIWKKDPQRLLNHYVSVAKGDPKK. 253
18 -16.600GD14186A YP_001299287.1 388212 Crystal|NMR-2008-04-09  ali follow..  19  31....................................SYNSYLIDDEMVALVDTVDVCYFEVYLKKIRSIIGDKPINYLIINHMEPDHSGSISLIKQYNIVIVGNKKTFEMIEG-GVGGERYVVGEGDFLALGHHRLRFSLIPMVHWPETMVTFDETEGILFSGDAFGCFGALNGGVVDTN-VGKYGAPVQKALQKLQKITTVCSTHGPV....................... 224
19 -14.700TM1162 TM1162 283028 Crystal|NMR-2002-09-14  ali follow..  15  7....................................GHAVVLIEGKKNIIID----PFISGNPVCPVKLEGLPKIDYILVTHGHGDHLGDAVEIAKKDATVISNYEICHYLGKKGVKTHAMHIGGSYLFDFGRVKMTPAVHGSGILDGDSMIYIEGKKIYHAGDTGLTREMELLAEIGGNFVMDVEDAVRAAVMI--KPKKVVPMH.......................... 190
20 -13.900SP13918A ZP_03458960.1 407444 Purified-2010-09-29  ali follow..  10  110...........AFERVLDGVKSSTVENGTAQIWLLYNMGYIIKTPSGCFGIDI----------SHRWAEEFAPYLDFLCVTHKHSDHY--IQAMYDLDKPVLSNYLQPVASY-------PFYSKKSEEYTIGNFKIRTC--ITNHNEADCGDDAGGLTLIHTGDSNFKPVIPRYAPNALTENDIIGTGTGQV-----TPDYVLLSHVLELSHADEEDSRWTVQSAWERASK. 336
21 -13.900GS13918A NP_809107.1 384839 Selected-2007-09-11  ali follow..  110...........AFDRVMDGIENSKVENGTAEIWLLYNMGYIVKTPSGCFAID----------ISHRWAKELAPYIDFLCVTHKHSDHYN-IQAMFDLDKPVLSNYLKDTTYP--------YTAKGDKDYEIGKFKIRTCITDHNNSGLSNFVTIGNFVFMHVGDSNFKTEQ-LIPRYAPNALTENNILGTGAGQVQP--DYVLLSH.......................... 304
22 -13.700GS0207A YP_001302908.1 384386 PDB-2009-11-06  ali follow..  10  41..................................IKHGSLMLTYDNHSIQVDPVSEYADYTTF---------PKADIILITHEHGDHLDAIQAVEKSDTEIIANENSQKKLGKGKVLK-----NGDTDTSISYMKIEAVPA-PRHRDNGYILTFDGLRVYIAGDTEDIPEMKDLKDIDIAFLMTVSQAAKAARMFSP--KILYPYHYGDTKIGELKDALK............ 229
23 -13.200PU1679C NP_247422.1 381581 Purified-2007-10-25  ali follow..  21......................................SALIEINNKRILFDAGQNSITLRENLRLFNEKEG--FDYIVLSHGHYDHCDGLKYVIEINGKVIAHKDALEIIEEPYKIDKDIIVSGYVPREYEYEMEEFQCIKDGKRVKDE---VNDDMFLIAKGILITGCS-----------SGIINVVEYGKKLSE-IKGVLGGHLVGVSDNYLNRIVDYFKSQDFWI... 225
24 -12.100PU1679B YP_753611.1 381520 Purified-2007-11-06  ali follow..  12  2.........NAVISILVENTTPSPSLIGEYG-------SALVEVDERKILFDTGSSDALFKNAENL--GVKLEEVEALVISHGHFDHTSAVIPFLQGPKKLYLHPGI-----SQRYLQGKKGLGPNIGCPFEPEDLVKNGAEIIFIDSFSEI---MPGVFISGEILLVDHPEGLIIISGCAHSGMINTIEYIREKTGRSKIFIGGHLITASEDRLAQTIAVLKMM....... 238
25 -11.800MA2439A NP_057291.1 399960 Purified-2009-03-27  ali follow..  15  2SAIPAEESDQLLIRPLG-------------AGQEVGRSCIILEFKGRKIMLDCGIHPGEGMDALPYIDLIDPAEIDLLLISHFHLDHCGALPWFLQK--RTFMTHATKAIVSNISADDMLYTETDHEVKEVAGIKFWCYHAG--HVLGAAMIEIAGVKLLYTGDIIESTYGTHIHEKREEREARFCNTVHDIVNR--GGRGLIPVFALGRAQELLLILDEYWQNHPELHDIP 267
26 -11.700GS13936A YP_001303382.1 384870 Purified-2008-06-17  ali follow..  13  57...................................SESMFLIFPDGTTMLLDCGDHNAVGEWISRYVRRPQKDYVDYMMLTHYHSDHGGNNKFYYLSGFSQAAEYLTFGKAFDRCWPEAADAFEHMKDFAHKKMEIEKFCLGETNNGMSLGMIFTDFKFYTAGDF---------SDGWELPNGKRFEIEDAIADVVEPVSVAKINHGHKSM------TDKLVAALRPRVV.. 333
27 -11.500TM0663 TM0663 282535 Purified-2004-02-02  ali follow..  11  7.............................DGHRNIGGNKIRVVDSENDFLLDFGLNPRTGKILHDLLKFEDPVNHAFLFLSHAHADHT-GMVGLIDEKIPLLMTGETFAVMRASKNIEFNDDLTVVDVNSLWKNELFVEPVY--HSVIGAAGLADDLWLAYTGDFRTGPETAWLDTLGEKRLALSLRTSRFFENLKDKRVLIVEGTRVTREENIENTEKDVFENAMRVFRG. 300
28 -11.500TT10477A YP_012016.1 404703 Selected-2009-08-14  ali follow..  12  101.AKGSYDSGLASIKDLIPNDLEKAWEIQKKLALHPENPGGFSCGTKHKYLLDTGWSYDWMEKSFKREKMLQAREIEALFISHEHWDHFWGLPVTMKNRIPLYVHDGFIKDSGYKGTPVIQKEPMRQIIPGMAVLKFDVPIINRVFGETSLAFNVKDKGVLISGC-------------CHQGILQMADFAYTDLKYDNDRFYGIYGHPFEDWDPKYDDLVISLAKWNFERIGC 343

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Slabinski L, Jaroszewski L, Rodrigues AP, Rychlewski L, Wilson IA, Lesley SA, Godzik A. The challenge of protein structure determination--lessons from structuralgenomics. Protein Sci. 2007 Nov;16(11):2472-82.