current user: public

anford Burnham Prebys Medical Discovery Institute
We are hiring bioinformatics experts and software developers. Join us!

Query: 2r2d_A mol:protein length:276 Zn-dependent hydrolases, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .
# Score Template Links and tools%idFirst MGNKLFVLDLGEIRVDENFIIANSTFVTPQKPTVSSRLIDIPVSAYLIQCTDATVLYDTGCHPECMGTNGRWPAQSQLNAPYIGASECNLPERLRQLGLSPDDISTVVLSHLHNDHAGCVEYFGKSRLIAHEDEFATAVRYFATGDHSSPYIVKDIEAWLATPRNWDLVGRDERERELAPGVNLLNFGTGHASGMLGLAVRLEKQPGFLLVSDACYTATNYGPPARRAGVLHDTIGYDRTVSHIRQYAESRSLTVLFGHDREQFASLIKSTDGFYELast
1 -103.0002r2d_A mol:protein length:276 Zn-dependent hydrolases  ali model  100  1MGNKLFVLDLGEIRVDENFIIANSTFVTPQKPTVSSRLIDIPVSAYLIQCTDATVLYDTGCHPECMGTNGRWPAQSQLNAPYIGASECNLPERLRQLGLSPDDISTVVLSHLHNDHAGCVEYFGKSRLIAHEDEFATAVRYFATGDHSSPYIVKDIEAWLATPRNWDLVGRDERERELAPGVNLLNFGTGHASGMLGLAVRLEKQPGFLLVSDACYTATNYGPPARRAGVLHDTIGYDRTVSHIRQYAESRSLTVLFGHDREQFASLIKSTDGFYE 276
2 -81.3002br6_A mol:protein length:252 AIIA-LIKE PROTEIN  ali model follow..  24  1MDMKLYFIPAGRCMLDHSSVNSALT---------PGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTVEGQILPKMTEEDRIVNILKRVGYEPDDLLYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKEC---------------LPHLNYKIIEGDYEVVPGVQLL-YTPGHSPGHQSLFIKTEQSGSVLLTIDASYTKENFEDEVP--FAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI.. 252
3 -81.1003aj3_A mol:protein length:274 4-pyridoxolactonase  ali model follow..  24  1MSTKVYLLDGGSLVLDGYHVFWNRG---------PGGEVRFPVYSILIEHAEGRFLIDTGYDYDHVMKVLPF-------EKPIQEKHQTIPGALGLLGLEPRDIDVVVNSHFHFDHCGGNKYFPHAKKICHRSEVPQACNPQPFEHLGYSDLSFSAEAAEARGATAQLFEGIDGDVDLARGVKLI-STPGHSIGHYSLLVEFPRRKPILFTIDAAYTQKSLETLCQAA-FHIDPVAGVNSMRKVKKLAEDHGAELMYSHDMDNFKTYRTGTQFY.. 267
4 -80.9003dha_A mol:protein length:254 N-Acyl Homoserine Lactone Hydrolase  ali model follow..  24  7.VKKLYFIPAGRCMLDHSSVNSALT---------PGKLLNLPVWCYLLETEEGPILVDTGMPESAVNNEGLFNGTVEGQILPKMTEEDRIVNILKRVGYEPDDLLYIISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKEC---------------LPHLNYKIIEGDYEVVPGVQLL-YTPGHSPGHQSLFIETEQSGSVLLTIDASYTKENFEDEVP--FAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI.. 254
5 -56.7001ztc_A mol:protein length:221 hypothetical protein TM0894  ali model follow..  20  1.........MGSDKIMELKILVTGGNVF-----VPGRLNAHFSTVVYLEHKDRRIIIDPGNLSSM----------------------DELEEKFSELGISPDDITDVLFTHVHLDHIFNSVLFENATFYVHEVYKTKNYLSFGTIVGRIYSK--------VISSWKNVVLLKGEESLFDEKVKVF-HTPWHAREHLSFLLDTENAGRVLITGDITPNRLSYYDIIKG----YGSVQVKNFLDRVGRID-----LLVFPHDAPLKPEVKK....... 215
6 -49.3004v0h_A mol:protein length:266 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROT  ali model follow..  20  18.PYSVVVLLQGAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEAARGPILVDTGGPWA----------------------REALLGALAGQGVAPGDVTLVVGTHGHSDHIGNLGLFPGAALLVSHDFCLPGGRYLPHGL------------------------GEGQPLRLGPGLEVW-ATPGHGGQRDVSVVVATALGTVVVAGDVFERDGDED---SWQALSEDPAAQERSRKRVLVVAD----VVVPGHGP............... 233
7 -46.7003esh_A mol:protein length:280 Protein similar to metal-dependent hydrolase  ali model follow..  18  6..ISIHYLNGGNTKMDGGAMFGPKPLWSKQYNANERNQINLPTHPILIQTAQYNLIIDAGIGNGKLSE--------KQLRNFGVDEESHIIADLANYNLTPKDIDYVLMTHMHFDHAAGLAIFENAIHVVQQDEWHEFIAP--NIRSKSTYWDKNKGDYS------NKLILFEKHFEPVPGIKMQH-SGGHSFGHTIITIE-SQGDKAVHMGDIFPTTAHKNPLWVTAY--DYPMQSIREKERMIPYFIQQQYWFLFYHDE............... 253
8 -40.5004zo2_A mol:protein length:294 Acylhomoserine lactonase  ali model follow..  15  13.ELELFILTDGYIHEENLISFVAELKTILKDNFRADHYIDMAINILLVKTKEKLILMDTGMGIFADERTGF------------------LLKSLQKAGFSAHDITDIFLSHAHPDHIGGVLVFPNASIFISKIEHDFWINASIKDFNNSALKAHPERLNQIIPALQPKLKFYDLNKTLYSHFNFQ-LAPGHTPGLTVTTIS-SGNEKLMYVADLIHSDVLFPHPDWGFSGDTDLDIATASRKKFLKQLADTKARAFTSHLP--LGFTKVKAPGF.. 285
9 -40.1004le6_A mol:protein length:324 Organophosphorus hydrolase  ali model follow..  19  44.DFEVTALYDGYVDLPASLLKKDLQSLLARMFVASEKGVQTAVNAYLINTGDNLVLIDTGAAQCFGPTLGV------------------VQTNLKASGYQPEQVDTVLLTHLHPDHACGLPAYPNATVEVPQAEAEFWLDEATMAKAPEGMMFKMAQQAVAPYAKMNKLKPYKTEGELLPGVSLV-ASPGHTPGHTSYLFK-SGGQSLLVWGDILLNHAQFAKPEVVFEFDVDSDQARQSRQRILAEAATDKLWVAGAHLP--LGHVRKEAQGY.. 310
10 -40.0004o98_A mol:protein length:337 organophosphorus hydrolase  ali model follow..  19  44.DFEVTALYDGYVDLPASLLKKDLQSLLARMFVASEKGVQTAVNAYLINTGDNLVLIDTGAAQCFGPTLGV------------------VQTNLKASGYQPEQVDTVLLTHLHPDHACGLPAYPNATVEVPQAEAEFWLDEATMAKAPEGMMFKMARQAVAPYAKMNKLKPYKTEGELLPGVSLV-ASSGHTPGHTSYLFK-SGGQSLLVWGDILINHAQFAKPEVVWEFDVDSDQARQSRQRILAEAATDKLWVAGAHLP--LGHVREEAQGY.. 310
11 -39.7004xuk_A mol:protein length:291 Putative hydrolase  ali model follow..  13  13.DVQITALLDGTNFMSPNLFKQQVHEILKKYYADQEKGVQTSINAFLVNIGKSLILIDSGAASCFGSHLGS------------------VLSNLKASGYQPEQVDTILLTHLHPDHVCGIANFPNATVYVSNDEASFWLDPKQAAKLPKEKQANYLGTVEKIKQAIAPYQAKQKLGDDIQGFKVI-NTAGHTPGHFSYELK-TKGESIVFIGDIVHSHTQFDRPETAIEYDIDPKKAVETRLKQFANFAKNGQTIAAPHYSADGKSYQWIPIHFKD 291
12 -39.6001p9e_A mol:protein length:331 Methyl Parathion Hydrolase  ali model follow..  16  54.DFEITALSDGTVALPVDKRQPAPKTQSALAKSFQKAPLETSVTGYLVNTGSKLVLVDTGAAGLFGPTLGR------------------LAANLKAAGYQPEQVDEIYITHMHPDHVGGLLAFPNAVVRADQKEADFWLSQTNLDKAPDDEFFKGAMASLNPYVKAGKFKPFSGNTDLVPGIKAL-ASHGHTPGHTTYVVE-SQGQKLALLGDLILVAAQFDDPSVTTQLDSDSKSVAVERKKAFADAAKGGYLIAASHLS--IGHIRAEGKGY.. 318
13 -38.4004p62_A mol:protein length:295 Metallo-beta-lactamase AIM-1  ali model follow..  14  58..........................................ISALLVTSDAGHILVDAATPQA----------------------GPQILANIRALGFRPEDVRAIVLSHEHFDHAGSLAELQKAPVYARAPAIDTLKRGLPDRTDPQFEVAEPVAP-----VANIVTLADDGVVSVGPLALTAVASPGHTPGGTSWTWRSCEGDQMVYADSLTAISDDVYRYSDDAAHPGYLAAFRNTLARVAALDCD---ILVTPHDTTACRRYAQGARQRLE 286
14 -38.3001sml_A mol:protein length:269 PROTEIN (PENICILLINASE)  ali model follow..  19  38..........................................LTALLVQTPDGAVLLDGGMPQMA----------------------SHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRAKVAANAESAVLLARGGSDDLHFG-------DGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCD---VLLTPHPGASNWDYAAGARAGAK 242
15 -37.9004awy_B mol:protein length:303 METALLO-BETA-LACTAMASE AIM-1  ali model follow..  14  58..........................................ISALLVTSDAGHILVDAATPQA----------------------GPQILANIRALGFRPEDVRAIVFSHEHFDHAGSLAELQKAPVYARAPAIDTLKRGLPDRTDPQFEVAEPVAP-----VANIVTLADDGVVSVGPLALTAVASPGHTPGGTSWTWRSCEGDQMVYADSLTAISDDVFRYSDDAAHPGYLAAFRNTLARVAALDCD---ILVTPHDTTACRRYAQGARQRLE 286
16 -36.6001jt1_A mol:protein length:263 FEZ-1, class B3 metallo-beta-lactamase  ali model follow..  14  25..........................................LASYLIVTPRGNILINSDLEANV----------------------PMIKASIKKLGFKFSDTKILLISHAHFDHAAGSELIKQAKYMVMDEDVSVILSGGKSDFHYANDSSTYFTQ-----STVDKVLHDGERVELGGTVLTAHLTPGHTRGCTTWTMKLKDHGQAVIIGSIGVNPGY--KLVDNITYPKIAEDYKHSIKVLESMRCD---IFLGSH................. 215
17 -36.4003lvz_A mol:protein length:294 Blr6230 protein  ali model follow..  17  55..........................................IAVYVIKTSQGLILMDTAMPQST----------------------GMIKDNIAKLGFKVADIKLILNTHAHLDHTGGFAEIKKAQLVAGERDKPLLEGGYYPGD-------EKNEDLAFPAVKVDRAVKEGDRVTLGDTTLTAHATPGHSPGCTSWEMTVKDGKEDREVLFFCSGTVALNRLVGQPTYAGIVDDYRATFAKAKAMKID---VLLGPH................. 242
18 -36.3005iqk_A mol:protein length:271 beta-lactamase Rm3  ali model follow..  13  31..........................................LSSVLVTSPQGHVLIDGGLPESA----------------------PKIIANIGALGFRIEDVKLILNSHGHIDHAGGLAELQRALVAASPSAALDLASGEVGPDDPQYHALPKYPP-----VKDMRLARDGGQFNVGPVYLTAHATPGHTPGGLSWTWQSCDGPNMVYADSINAVSRPGFKFSASSEYPNALADLRHSFETLEKLPCD---VLISAH................. 223
19 -35.4005aeb_A mol:protein length:272 LRA-12  ali model follow..  14  38..........................................LACYLITTKQGNIIVNTGLAASA----------------------LQIKNNIKALGFKLTDTKILLTTQAHYDHLGAMAEIKKAKLMADEGDATVMADGGSSDYAFGG------HGSMFEPIIADRLLHDKDTIQLGDTKLVMLHHPGHTKGSCSFLFDTKDEQ-ILIANMPIVIEKKFSEVSSYPGIAKD---YAYTLQAMKNLSFD---IWVASHASQF............. 231
20 -35.3003vpe_A mol:protein length:262 Metallo-beta-lactamase  ali model follow..  13  26..........................................ISAVLLSSPQGHILVDGTTEKGA----------------------QVVAANIRAMGFKLSDVKYILSTHSHEDHAGGISAMQKATVLAGAANVDTLRTGVSPKSDPQFGSLSNFPG-----SAKVRAVADGELVKLGPLAVKAHATPGHTEGGITWTWQSCEQG-VVFADSLTAVSADSYRFSDHPEVVAS---LRGSFEAVEKLSCD---IAIAAHPEVN............. 219
21 -34.4002q0j_A mol:protein length:321 Quinolone signal response protein  ali model follow..  16  36..........................................VPVFLLRGEASWALVEGGISRDA----------------------ELVWADLCRWVADPSQVHYWLITHKHYDHCGLLPRLPNVQVLASERTCQAWKSESAVRNRQLLRAEQRLPEACAWDALPVRAVADGEWLELGPRHRLVIEAHGHSDDHVVFYDVRRR---RLFCGDALGEFDEAEGVWRPL-VFDDMEAYLESLERLQRL--PTLLQLIPGH................. 235
22 -33.2003adr_A mol:protein length:261 Putative uncharacterized protein ST1585  ali model follow..  16  2PCRGLHSIPAGPVEFPEI------------------------ATVYVMCGEKLTVMIDAGVSNSIAD-------------------------------SFLDKLDYIVLTHLHIDHIGLLPELYKAKVLVKSGFKKYLTSEESAEKVLGDLYYVYGGLEKKLDQDKVIEVEGNEEFDLGGYRMRLIYTPGHARHHMSVLVD------FLFTGDSAYFNGVVIPTTPPVI---DYKMYMESLKRQIELKPK---VVGFAH................. 207
23 -29.6002zo4_A mol:protein length:317 Metallo-beta-lactamase family protein  ali model follow..  20  12.....................................PVPIPVNLYLLQGAGEVALVDTALGTR--------------------AARGALELHLAELGLCFQDVKTILLTHHHPDHYGLSGFFEGARVFLHEEEFARGHRFWREPEAFAEASWRLFLDHGTPEGALQGIRETQNPLPLRDGEALVLWTPGHADGHAAFYLEEEG---VLLAGDALLEKVSPNVGLWAYTRENPLKDFLRSLDRLADLGAR---VAYAGHF................ 234
24 -28.9002zwr_A mol:protein length:207 Metallo-beta-lactamase superfamily protein  ali model follow..  18  10.......................................PLQENAYLVETGEGPVLIDPG------------------------DEPEKLLALFQTTGLIPL---AILLTHAHFDHVGAVAPLVELPVYLHPLDLPLYEGADLAARAWG----------------LAIPKPPLPVRPLEEGMRLVLHLPGHSPGHVAFYDPEGA---QVFSGDLLF-RGSVGRYDLPGA---DPKALFASLKRLLSLPP--ETRVHPGHGPGTTLGLEARTNPFLT 201
25 -27.8002p97_A mol:protein length:201 Hypothetical protein  ali model follow..  15  17...................................NPARNIDFNGFAWIRPEGNILIDPV------------------------ALSNHDWKHLESLG----GVVWIVLTN---DHVRSAKEIADTKIAGPVAEKENF--------------------------PIYCDRWLSDGDELVPGLKVM-ELQGKTPGELALLLE----ETTLITGDLVRAYRAGGLEILPDEKLMNKQKVVASVRRLAALEKVE--AVLVGDGWSVFRDGRDRLKELVA 198
26 -27.6005a87_A mol:protein length:248 METALLO-BETA-LACTAMASE VIM-5  ali model follow..  15  49........................................YPSNGLIVRDGDELLLIDTAWGAK---------------------NTAALLAEIEKQIGLP--VTRAVSTHFHDDRVGGVDVLRKAGVATYASPSTRRLAEAEGNEIPTHSLEGLSS---------------SGDAVRFGPVELFYPGAAHSTDNLVVYVPSAN---VLYGGCAVL---ALSRTSAGNVADADLAEWPTSVERIQKHYPEAEV-VIPGHGLPGGLDLLQHTANVVT 239
27 -26.9004uwo_B mol:protein length:266 METALLO-BETA-LACTAMASE VIM-26  ali model follow..  15  67........................................YPSNGLIVRDGDELLLIDTAWGAK---------------------NTAALLAEIEKQIGLP--VTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEAEGNEIPTHSLEGLSS---------------SGDAVRFGPVELFYPGAAHSTDNLVVYVPSAN---VLYGGCAVLELSSTSAGNVADA---DLAEWPTSVERIQKHYPEAEV-VIPGHGLPGGLDLLQHTANVVK 257
28 -26.5002yz3_A mol:protein length:266 Metallo-beta-lactamase  ali model follow..  16  67........................................YPSNGLIVRDGDELLLIDTAWGAK---------------------NTAALLAEIEKQIGLP--VTRAVSTHFHDDRVGGVDVLRAAGVATYASPSTRRLAEVEGNEIPTHSLEGLSS---------------SGDAVRFGPVELFYPGAAHSTDNLVVYVPSAS---VLYGGCAIY---ELSRTSAGNVADADLAEWPTSIERIQQHYPEAQF-VIPGHGLPGGLDLLKHTTNVVK 257
29 -26.2002y87_A mol:protein length:265 METALLO-B-LACTAMASE  ali model follow..  14  66........................................YSSNGLIVRDADELLLIDTAWGAK---------------------NTVALLAEIEKQIGLP--VTRSISTHFHDDRVGGVDVLRAAGVATYTSPLTRQLAEAAGNEVPAHSLKALSS---------------SGDVVRFGPVEVFYPGAAHSGDNLVVYVPAVR---VLFGGCAVH---EASRESAGNVADANLAEWPATIKRIQQRYPEAEV-VIPGHGLPGGLELLQHTTNVVK 256
30 -25.9002nze_A mol:protein length:222 Beta-lactamase II  ali model follow..  12  34........................................VPSNGLVLNTSKGLVLVDSSWDDKLT---------------------KELIEMVEKKFQKR--VTDVIITHAHADHIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMK-----------------VETFYPGKGHTEDNIVVWLPQYN---ILVGGSLVKSTSAKDLGNVADA---YVNEWSTSIENVLKRYRNINA-VVPGHGEVGDKGLLLHTLDLLK 222
31 -25.5001x8h_A mol:protein length:228 Beta-lactamase  ali model follow..  14  27..............................................VYFGAKGVTVVGATWTPDTA---------------------RELHKLIKRVSRKP--VLEVINTNYHTDRAGGNAYWKSIGAKVVSTR-QTRDLMKSDWAEIVAFTRKGLPEYPDLPLVLPNVVHDGDFTLQEGKVRAFYAGPAHTPDGIFVYFPDEQ---VLYGGCILK-------EKLGNLSFADVKAYPQTLERLKAMKLPIKT-VIGGHDS............... 206
32 -25.5004gyq_A mol:protein length:243 Beta-lactamase NDM-1  ali model follow..  11  46........................................VASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGAA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 240
33 -25.3004tyf_A mol:protein length:231 NDM-4  ali model follow..  16......................APNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKA---KSLGNLGDADTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 228
34 -25.3003fcz_A mol:protein length:222 Beta-lactamase 2  ali model follow..  11  34........................................VPSSGLVLNTSKGLVLVDSSWDDKLT---------------------KELIEMVEKKFQKR--VTDAIITHAHADRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMK-----------------VETFYPGKGHTEDNIVVWLPQYN---ILVGGCLVKSTSAKDLGNVADA---YVNEWSTSIENVSKRYRNINA-VVPSHGEVGDKGLLLHTLDLLK 222
35 -25.1003rkk_A mol:protein length:237 Beta-lactamase NDM-1  ali model follow..  22......................APNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGDA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 234
36 -25.1004rl2_A mol:protein length:246 Beta-lactamase NDM-1  ali model follow..  10  49........................................VASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGDA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 243
37 -25.1005a5z_A mol:protein length:251 BETA-LACTAMASE NDM-1  ali model follow..  10  46........................................VASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQL-----------APQEGMVAAQHSLTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGDA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 240
38 -25.0002uyx_A mol:protein length:228 BETA-LACTAMASE II  ali model follow..  11  40........................................VPSNGLVLNTSKGLVLVDSSWDDKLT---------------------KELIEMVEKKFQKR--VTDVIITHAHASRIGGIKTLKERGIKAHSTALTAELAKKNGYEEPLGDLQTVTNLKFGNMK-----------------VETFYPGKGHTEDNIVVWLPQYN---ILVGGCLVKSTSAKDLGNVADA---YVNEWSTSIENVLKRYRNINA-VVPGHGEVGDKGLLLHTLDLLK 228
39 -24.9003q6v_A mol:protein length:233 Beta-lactamase  ali model follow..  14  30..............................................VYIGTDGITIIGATWTPETA---------------------ETLYKEIRKVSPLP--INEVINTNYHTDRAGGNAYWKTLGAKIVATQ-MTYDLQKSQWGSIVNFTRQGNNKYPNLEKSLPDTVFPGDFNLQNGSIRAMYLGEAHTKDGIFVYFPAER---VLYGNCILK-------ENLGNMSFANRTEYPKTLEKLKGLIEQGELSIIAGHDT............... 213
40 -24.5003spu_A mol:protein length:265 Beta-lactamase NDM-1  ali model follow..  10  47........................................VASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGDA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 241
41 -24.5004bp0_A mol:protein length:250 METALLO-B-LACTAMASE  ali model follow..  11  38.............................................VAKMLDGTVVIVSSPFENL---------------------GTQTLMDWVAKT--MKPKKVVAINTHFHLDGTGGNEIYKKMGAETWSSDLTKQLRLEENKKDRIKAAEFYKNEDLKRRILSSHPVPADNVFDLKQGVEVSFPGPAHSPDNVVVYFPKKK---LLFGGCMIK------PKELGYLGDANVKAWPDSARRLKKFDAK---IVIPGHGEWGGPEMVNKTIKVAE 242
42 -24.4003l6n_A mol:protein length:219 metallo-beta-lactamase  ali model follow..  13  35..............................................YLVTKKGVVLFDVPWEKVQY---------------------QSLMDTIKKRHNLP--VVAVFATHSHDDRAGDLSFFNNKGIKTYATAKTNEFLKKDGKATSTEIIKTGKPYRIGGEE-----------------FVVDFLGEGHTADNVVVWFPKYN---VLDGGCLVKSNSATDLGYIKEA---NVEQWPKTINKLKAKYSKATL-IIPGHDEWKGGGHVEHTLELLN 217
43 -24.3004f6h_A mol:protein length:236 Beta-lactamase  ali model follow..  13  13......................DEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAK---------------------DTEKLVTWFVERG---YKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTN-------------------ELLKKDGKVQATNSFSGVNYWLVK-IEVFYPGPGHTPDNVVVWLPERK---ILFGGGF------IKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKL-VVPSHSE............... 199
44 -24.2004exs_B mol:protein length:272 Beta-lactamase NDM-1  ali model follow..  10  73........................................VASNGLIVRDGGRVLVVDTAWTDD---------------------QTAQILNWIKQEINLP--VALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNF-----------GPLKVFYPGPGHTSDNITVGIDGTD---IAFGGCLIKDSKAKSLGNLGDA---DTEHYAASARAFGAAFPKASM-IVMSHSAPDSRAAITHTARMAD 267
45 -23.9004wd6_A mol:protein length:233 Metallo-beta-lactamase  ali model follow..  12  13......................KENIFLHTSYSRVNGFGLVSSNGLVVIDKGNAFIVDTPWSDR---------------------DTETLVHWIRKNG---YELLGSVSTHWHEDRTAGIKWLNDQSISTYATTSTNHL-------------------LKENKKEPAKYTLKGNESTLVDGIEVFYPGGGHTIDNVVVWLPKSK---ILFGGCFVR---SLDSEGLGYTGEAHIDQWSRSAQNALSRYSEAQI-VIPGHGKIGDIALLKHTKSLAE 217
46 -23.6002ynt_B mol:protein length:233 GIM-1 PROTEIN  ali model follow..  12  31........................................VDSNGLVVLDNNQAYIIDTPWSEEDTK------------------------LLLSWATDRGYQVMASISTHSHEDRTAGIKLLNSKSIPTYTSELTK-------------------KLLAREGKPVPTHYFKDDEFTLGNGIELYYPGAGHTEDNIVAWLPKSK---ILFGGCLVR---SHEWEALGYVGDASISSWADSIKNIVSKKYPIQM-VVPGHGKVGSSDILDHTIDLAE 217
47 -23.5001znb_A mol:protein length:232 METALLO-BETA-LACTAMASE  ali model follow..  14  35........................................VPSNGMIVINNHQAALLDTPINDAQT---------------------ETLVNWVADSLHAK--VTTFIPNHWHGDCIGGLGYLQKKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMP-----------------LQCYYLGGGHATDNIVVWLPTEN---ILFGGCMLKDNQATSIGNISDA---DVTAWPKTLDKVKAKFPSARY-VVPGHGDYGGTELIEHTKQIVN 223
48 -23.4001a7t_A mol:protein length:232 METALLO-BETA-LACTAMASE  ali model follow..  14  35........................................VPSNGMIVINNHQAALLDTPINDAQT---------------------EMLVNWVTDSLHAK--VTTFIPNHWHGDCIGGLGYLQRKGVQSYANQMTIDLAKEKGLPVPEHGFTDSLTVSLDGMP-----------------LQCYYLGGGHATDNIVVWLPTEN---ILFGGCMLKDNQTTSIGNISDA---DVTAWPKTLDKVKAKFPSARY-VVPGHGNYGGTELIEHTKQIVN 223
49 -23.4001m2x_A mol:protein length:223 class B carbapenemase BlaB-1  ali model follow..  15  31..............................................YLVTDKGVVVIDCPWGEDKF---------------------KSFTDEIYKKHGKK--VIMNIATHSHDDRAGGLEYFGKIGAKTYSTKMTDSILAKENKPRAQYTFDNNKSFKVGKSE-----------------FQVYYPGKGHTADNVVVWFPKEK---VLVGGCIIKSADSKDLGYIGEA---YVNDWTQSVHNIQQKFSGAQY-VVAGHDDWKDQRSIQHTLDLIN 213
50 -23.2004ubq_A mol:protein length:229 Beta-lactamase  ali model follow..  14  14......................EEGVYVHTSFEEVNGWGVVSKHGLVVLVNTDAYLIDTPFTAT---------------------DTEKLVNWFVERG---YKIKGTISSHFHSDSTGGIEWLNSQSIPTYASELTN-------------------ELLKKDGKVQAKNSFSGVSYWLVK-IEVFYPGPGHTQDNVVVWLPEKK---ILFGGCFVK------PDGLGNLGDANLEAWPKSAKILMSKYVKAKL-VVSSHSEIGDASLLKRTWEQAV 215
51 -22.9005acp_A mol:protein length:250 GIM-1 PROTEIN  ali model follow..  12  48........................................VDSNGLVVLDNNQAYIIDTPWSEEDTK------------------------LLLSWATDRGYQVMASISTHSHEDRTAGIKLLNSKSIPTYTSELTK-------------------KLLAREGKPVPTHYFKDDEFTLGNGIELYYPGAGHTEDNIVAWLPKSK---ILFGGCLVRSHEREGLGYVGDA---SISSWADSIKNIVSKKYPIQM-VVPGHGKVGSSDILDHTIDLAE 234
52 -20.3005i0p_A mol:protein length:366 Beta-lactamase domain protein  ali model follow..  14  35.....................................RMPLPINLWLLRDQAGWTIVDCGISSE---------------------AIRTHWEQIFDRHLDGLPVLRVLVTHCHPDHFGLANWLCEVRLWMTLGEYMFGAADHFARHGLTDPAALDKLRSRRSYYSDLVPAVPPRYRRLREGDAVVVTGYGHSPEHCALH---SEADGVLISGDMVLPRISTNVSVFDLEPEANPALYLESLGRYETM--APDTLVLPSHG................ 272
53 -20.2002p4z_A mol:protein length:284 Metal-dependent hydrolases of the beta-lactam  ali model follow..  13  29............................................SLLLKKGNKEIVVDTG-------------------------QSENFIKNCGLMGIDVGRIKKVVLTHGHYDHIGGLKGLPEVKIYTHKEILNKKYAMRKGGQFEEIGFDLSF------EKYKNNFVLIDKDAEIEEGFYVITNTDITYD-DEVFVVVKEEDGINVVTGNILETARNRFGVSYIKSLIGGFHLRGMEEEKVKDIEEYGVKKVLTGH................. 249
54 -19.9002xf4_A mol:protein length:210 HYDROXYACYLGLUTATHIONE HYDROLASE  ali model follow..  16  10.......................................AFSQNCSLIEQTRLAALVDPG------------------------GDAEKIKQEVDASGVT---LMQILLTHGHLDHVGAASELAQVPVIGPEKEDEFWLQGLPAQSRMFGLDE-------CQPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGH---VVFFDEQSQLLISGDVIF-KGGVGRSDFPRG---DHTQLIDAIKR-KLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQ 209
55 -19.3004ad9_A mol:protein length:289 BETA-LACTAMASE-LIKE PROTEIN 2  ali model follow..  17  32..........................................TNTYLVGTGPRRILIDTG------------------------AIPEYISCLKQALTEFNTAIQEIVVTHWHRDHSGGIGDICKSINNDTTYCIKKLPRNPQREEIIGNGEQQYVY-------------LKDGDVIKTEGATLVLYTPGHTDDHMALLLEEEN---AIFSGDCILGEGT--------TVFEDLYDYMNSLKELLKIKAD---IIYPGHGP............... 202
56 -18.9003g1p_A mol:protein length:258 Protein phnP  ali model follow..  11  1MSLTLTLTGTGG---AQGVPAWGCECAACARARRSPQYRRQPCSG-VVKFNDAITLIDAGLHD-------------------------------LADRWSPGSFQQFLLTHYHMDHVQGLFPLRGDPIPVYGPPDEQGCDDLFKHPGLLDFSHTVEPFVVFD----------------LQGLQVTPLPLNHSKLTFGYLLE-TAHSRVAWLSDTAGLPEKTLKFLRNNQPQVNHCDLNTVLALNQVIRSPRVILTHISHQFDAWLMENALPSGFFD 245
57 -18.7001xm8_A mol:protein length:254 glyoxalase II  ali model follow..  14  13...........................................YAYILHDEDTVGVVDPS-------------------------EAEPIIDSLKRSGRN---LTYILNTHHHYDHTGGNLELKDAKVIGSAMDKDRI-------------------------PGIDMALKDGDKWMFAGHEVHVMDTPGHTKGHISLYF---PGSRAIFTGDTMFSLS----------FEGTPKQMLASLQKITSLPD--DTSIYCGHE................ 170
58 -18.5001zkp_A mol:protein length:268 hypothetical protein BA1088  ali model follow..  15  36.........................................ATSGYLFEHDGFRLLVDCGSG---------------------------VLAQLQKY-ITPSDIDAVVLSHYHHDHVADIGVLQYARLITSATKGQLPELPI-----YGHTFDENGFHSLTHEPHTKGIPYNPEETLQIGPFSISFLKTVHPVTCFAMRIT-AGNDIVVYSADSSYIPEFIPFTKDADLFICECNAGHMNSTEVASIAKDANVELLLTHLPHNPADLVTEAKQIFS 248
59 -18.3001qh3_A mol:protein length:260 PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE)  ali model follow..  13  8..............................................ALTDNYMYLVIDDETKEAAIVDPV---------------QPQKVVDAARKHGVK---LTTVLTTHHHWDHAGGVKLESGLKVYGGDDRIGALTHKIT----------------------------HLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSPAVFTGDTLFVAG--------KFYEGTADEMCKALEVLGRLPP--DTRVYCGHE................ 174
60 -18.1002p18_A mol:protein length:311 Glyoxalase II  ali model follow..  11  30..............................................TLKDNFSYLINDHTTHTLAAVDVNADYKPILTYI-----EEHLKQQGNADVTYT---FSTILSTHKHWDHSGGNAKLKAELEAMNSTVPVVVVGGANDSIPAVTKPVRE-----------------GDRVQVGDLSVEVIDAPCHTRGHVLYKVQHPNDGVALFTGDTMFIAG-------------DEKDMCRAMEKVYHIHKGKVTFIFPGHE................ 221
61 -17.6002ycb_A mol:protein length:636 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACT  ali model follow..  14  186...................................GGFREVGRSCLYLQTPNSRVLLDCGVNVAG-------------------GDDKNSYPYLNVPEFTLDSLDAVIITHAHLDHSGFLPYLTAPTRDLMTLLQLDHIDIAHREDEPLPFNVKHVKKSVKHTITLDY----GEVTDIAPDIRLTLHNAGHILGSAMAHLHIGDGQNMVYTGDFKYEQSRLLEAAANRFPRIETLVMESTVKTIYSTLRRGGKILIPVFAVGRAQELMIVLEEYIR 433
62 -17.6004ysb_A mol:protein length:233 Metallo-beta-lactamase family protein  ali model follow..  16  13..........................................TYTYLIGDEATRVLID-----------------------PVLEQVDRDLQMVAELDLT---LTHVFDTHVHADHITASGALREATVVGSVNGASCA----------------------------NVQVRHGDEVRVGQLVFQVLATPGHTDDSISYLL-----GDRVFTGDALLVRGNGRTDFQNG----NASQLYDSLTR-VLFTLPDETLVYPGHD................ 171
63 -17.4004chl_A mol:protein length:238 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL  ali model follow..  14  19..........................................TFTYLLGDRESRVLIDP-----------------------VLETAPRDAQLIKELGLR---LLYAVNTHCHADHITGSGLLRSGCQSVISR---------------------------LSGAQADLHIEDGDSIRFGRFALETRASPGHTPGCVTFVL---NDHSMAFTGDALLIRGCGRTDFQQG----CAKTLYHSVHE-KIFTLPGDCLIYPAHD................ 180
64 -17.2003af5_A mol:protein length:651 Putative uncharacterized protein PH1404  ali model follow..  13  195...................................GGFREVGRSALLVQTDESFVLVDFGVNVAMLNDPYKAFPHFDAPE--------------FQYVLREGLLDAIIITHAHLDHCGMLPYLTPPTRDLMVLLQKDFIEIQQSNGQDPLYRPRDIKEVIKHTITLDY----GEVRDISPDIRLTLHNAGHILGSAIVHLHIGNGLNIAITGDFKFIPTRLLEPANAKFPRLETLVMESTIEVIHNTIKRGGKVLIPAMAVGRAQEVMMVLEEYAR 448
65 -16.9002gcu_A mol:protein length:245 Putative hydroxyacylglutathione hydrolase 3  ali model follow..  13  15..........................................TFTYLLHPDKPALLID-----------------------PVDKTVDRDLKLIDELGLK---LIYAMNTHVHADHVTGTGLLKTGVKSVISKA---------------------------SGSKADLFLEPGDKVSIGDIYLEVRATPGHTAGCVTYVTG-QPQPRMAFTGDAVLIRGCGRTDFQEG----SSDQLYESVHS-QIFTLPKDTLIYPAHD................ 184
66 -16.5002xr1_A mol:protein length:640 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACT  ali model follow..  15  190...................................GGCKEVGRSCFLLSTPESRILIDCGVNVG--------------------SDENMTPYLYVPEVFPLNQIDAVIVTHAHLDHQGLVPLLTPPTRDLMVLLQLDYIDVAAKEGKKIPYESGMVAKTLKHTIPLD----YEEVTDIAPDIKLTFHNAGHILGSAISHFHIGDGLNVVFTGDYKYEKTRLFDPAVNKFPRVETVISEATYMVVKNTIERGGIAVIPAFAVGRSQEV......... 427
67 -16.3003h3e_A mol:protein length:267 uncharacterized protein Tm1679  ali model follow..  16  28............................................SVLVDS----VLFDTG-------------------------KSDVFLKNARKLGIDLPKD--VLISHGHYDHAGGLLYLSGKRVWLRKEALDQKYSGERY-------------DWNEVLYYNTGKFVIERITEIGKNMFLLGPANLRGK-DEQTLVVRTKEGLVVITGCSHRGIDNILLDIAEGGFHLLKSSDDEIEKIVKAFNELGVETVVPCH................. 230
68 -16.3002i7x_A mol:protein length:717 Protein CFT2  ali model follow..  10  17............................................GSVVRFDNVTLLIDPGWNPSK----------------------VSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLL-RIQVYATLPVINYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRY-DGLTLLAYNAGVCPGGSIWCISTYSEK-LVYAKRWNHTRDNLSTLMRPSAIITTLDRFGSSKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLF 266
69 -16.0002i7t_A mol:protein length:459 Cleavage and polyadenylation specificity fact  ali model follow..  11  18...................................GAGQEVGRSCIILEFKGRKIMLDCGIHPGL----------------------EGMDALPYIDLIDPAEIDLLLISHFHLDHCGAL------PWFLQKTSFKGRTFMTHATKAIYRWLLSDYVKVSNISADDMLYTETDLEESMVAGIKFWCYHAGHVLGAAMFMIEIAGVK-LLYTGDFSRQEDRHLMAAEIPNIKPDILIIESTCNTVHDIVNRGGRGLIPVFALGRAQELLLILDEYWQ 258
70 -14.9002qed_A mol:protein length:258 Hydroxyacylglutathione hydrolase  ali model follow..  12  20...........................................YIWVLTNDEGRVIVDPG-------------------------EAAPVLKAIAEHKWMPEAI-------FLTDHVGGVQHFPQMTVYGPAET---------------------------QDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYF-----SRPYLFCGDTLFSGG-------------TPSQMYQSLMKINSLPD--DTLICCAHE................ 169
71 -14.8004fek_A mol:protein length:262 Putative diflavin flavoprotein A 5  ali model follow..  11  41........................................TTSNSYVIE-GDKTAIIDP----------------------PVESFMKIYLEALQQT-VNLKKLDYVILGHFSPNRIPTFKALPQITFVCSLPAAGDLRAAFPDDNLNILPMRG------------------KETLDLGKGHVLFLPIP-RWPA---GLCTYDVQTQILYTDKIFGAHESFKEDQRYYFNCLMAPHAIHVEAALEKISDLQVRLYAVGHGPLVRTSLIALTQAYAD 248
72 -14.7003rpc_A mol:protein length:264 possible metal-dependent hydrolase  ali model follow..  12  14............................................TGKLTIKNTTFLIDPFLAPKDTYPGFEGTFNYQQRMP-MVDLPLSMDDLL-------SNVTAVVVTHTHLDHTAINSIPKSLPIFVQNTADKELITSQGFIDVRI----------IFESLEFNGITLRKTGGSHGTVEMYANPVLAPLAGDMGVIFEAADEPTVYLVGDTVWTSEKALLRFDPNVIIMNTGYAMGTKDIGRMVVRKPEAKIIAVH................. 226
73 -14.0002ohh_A mol:protein length:404 Type A flavoprotein fprA  ali model follow..  33........................................TTYNAYLVCGDEGVALIDN----------------------SYPGTFDELMARVEDAQVGMERVDYIIQNHVEKDHSGVLRRFPEAPIYCTEVAVKGLLKHYPSLREAEFMTVKT-----------------GDVLDLGGKTLTFLETP-HWPDSMFTLLDEDG---ILFSNDAF-CPQRLDREIPEYILMDAARKFYANFDEVKELGLLERIQMIAPSHGQIWTDPMKIIEAYTG 249
74 -13.9002dkf_A mol:protein length:431 metallo-beta-lactamase superfamily protein  ali model follow..  12  7...................................GAAREVTGSAHLLLAGGRRVLLDCGM------------------------QGKEEARNHAPFGFDPKEVDAVLLTHAHLDHVGRLPKL-RGPVYATRATVLLMEIVLEDALKVMDEPFFGPEDVEEALGHLRPLEYGEWLRL--GALSLAFGQAGHLPGSAFVVAQGEGRT-LVYSGDLGNREKDVLPD--PSLPPLADLVLAEGTEILEKTLSQGGKVLIPTFAVERAQEI......... 231
75 -13.8004ysk_A mol:protein length:294 Beta-lactamase domain protein  ali model follow..  14  19..........................................TISYLVMDRETRALIDSVLDYDPKS------------GRTCSASADRLVERVNELNAS---VRWVLETHVHADHLSAAAYLKEGHTAIGAH--------ITQVQKVFGALFNAEPGFARDGSQFDVLLEDEEGFRIGNLQARALHTPGHTPACMSFMIE-DAGEIAVFVGDTLFMPDYGTARCDFPG---DARTLYRSIRRLLAFPDQ--TRLFMCHD................ 213

FFAS is supported by the NIH grant R01-GM087218-01
1 0 8 9 4 2   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Ginalski K, Grishin NV, Godzik A., Rychlewski L. Practical lessons from protein structure prediction. Nucleic Acids Res. 2005 Apr 1;33(6):1874-91.