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anford Burnham Prebys Medical Discovery Institute
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Query: 4d02_A mol:protein length:479 ANAEROBIC NITRIC OXIDE REDUCTASE FLAVORUBREDO, from PDB0516

Results of FFAS03 search in PDB0516
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALKLCREHGREIARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFEELASEAKLast
1 -148.0004d02_A mol:protein length:479 ANAEROBIC NITRIC OXIDE REDUCTASE FLAVORUBREDO  ali model  100  1MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDAVLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALKLCREHGREIARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGKDVFEELASEAK 475
2 -114.0001ycf_A mol:protein length:398 Nitric oxide reductase  ali model follow..  40  3.PVAITDGIYWVGAVDWNIRYFHGPAFSTHRGTTYNAYLIVDDKTALVDTVYEPFKEELIAKLKQIKDPVKLDYLVVNHTESDHAGAFPAIMELCPDAHVLCTQRAFDSLKAHYFNYTIVKTGTSVSLGK-RSLTFIEAPMLHWPDSMFTYVPEEALLLPNDAFGQHIATSVRFDDQVDAGLIMDEAAKYYANILMPFSNLITKKLDEIQKINLAIKTIAPSHGIIWRKDPGRIIEAYARWAEGQGKAKAVIAYDTMWLSTEKMAHALMDGLVAGG--CEVKLFKLSVSDRNDVIKEILDARAVLVGSPTINNDILPVVSPLLDDLVGLRPKNKVGLAFGAYGWGGGAQKILEERLKAAKIELIPGPTVQWVPRGEDLQRCYELGRKIAARIAD................................................................................. 398
3 -112.0001e5d_A mol:protein length:402 RUBREDOXIN:OXYGEN OXIDOREDUCTASE  ali model follow..  33  3.ATKIIDGFHLVGAIDWNSRDFHGY-TLSPMGTTYNAYLVEDEKTTLFDTVKAEYKGELLCGIASVIDPKKIDYLVIQHLELDHAGALPALIEACQPEKIFTSSLGQKAMESHFWPVQVVKHGETLSLGK-RTVTFYETRMLHWPDSMVSWFADEKVLISNDIFGQNIAASERFSDQIPVHTLERAMREYYANIVNPYAPQTLKAIETLVGAGVAPEFICPDHGVIFRDQCTFAVQKYVEYAEQKPTNKVVIFYDSMWHSTEKMARVLAESFRDEG--CTVKLMWCKACHHSQIMSEISDAGAVIVGSPTHNNGILPYVAGTLQYIKGLRPQNKIGGAFGSFGWSGESTKVLAEWLTGMGFDMPTPVKVKNVPTHADYEQLKTMAQTIARALKAKLAA............................................................................. 402
4 -108.0002ohh_A mol:protein length:404 Type A flavoprotein fprA  ali model follow..  37  4AAKRISDGVYWTGVLDWDLRNYHGY---TLQGTTYNAYLVCDEGVALIDNSYPGTFDELMARVEDAVGMERVDYIIQNHVEKDHSGVLVELHRRFPEAPIYCTEVAVKGLLKHYAEFMTVKTGDVLDLGG-KTLTFLETPLLHWPDSMFTLLDEDGILFSNDAFGQHLCCPQRLDREIPEYILMDAARKFYANLITPLSKLVLKKFDEVKELGLRIQMIAPSHGQIWT-DPMKIIEAYTGWATGMVDERVTVIYDTMHGSTRKMAHAIAEGAMSEG--VDVRVYCLHEDDRSEIVKDILESGAIALGAPTIYDEPYPSVGDLLMYLRGLRTLTRKALVFGSMGGNGGATGTMKELLAEAGFDVACEEEVYYVPTGDELDACFEAGRKLAAEIRR................................................................................. 404
5 -107.0002q9u_A mol:protein length:414 A-type flavoprotein  ali model follow..  30  10.DQEMIPGVYWVGIVDWMVRIFHG--YHTDEGSSYNSYFIDDECPTVIDSVKYPFAEEWLSRIAACCPLDKIKYVVMNHAEGDHASSLKDHYHKFTNATFVCTKKCQEHLKILYATWLIVDDKYTLKIGK-RTLKFIPVPLLHWPDSTFTYCPEDKILFSNDGFGQHYATSRRWADECDVSHVMHLFKEYTANILGLFSAQMRKALEVAS--TVEIKYILSAHGVSWRGDMGLAIAEYDRWSKGQHQKKVTVVLDSMYGTTHRMALALLDGARSTG--CETVLLEMTSSDITKVALHTYDSGAVAFASPTLNNTMMPSVAAALNYVRGLTLKGKPAFAFGAFGWSNRAVPDIVAELRDCKADVYKGITFKFNYTEELLEQAYNAGVDLGKRAIAYCEKNAPKQ........................................................................ 414
6 -98.9001vme_A mol:protein length:410 Flavoprotein  ali model follow..  24  14.RIFDDPEIYVLRIDDDRIRYFEAV-WEIPEGISYNAYLVKNGANVLIDGWKGNYAKEFIDALSKIVDPKEITHIIVNHTEPDHSGSLPATLKTIHDVEIIASNFGKRLLEGFYKDVTVVKDGEEREIGG-KKFKFVMTPWLHWPDTMVTYL--DGILFSCDVGGGYLLPEILDSNESVVERYLPHVTKYIVTVIGHYKNYILEGAEKLSS--LKIKALLPGHGLIWKKDPQRLLNHYVSVAKGDPKKKVTVIYDSMYGFVENVMKKAIDSLKEKGFTVVYKFSDEERPAISEILKDIPDSEALIFGVSTYEAEIHPLMRFTLLEIIDKANYEKPVLVFGVHGWAPSAERTAGELLKETKFRILSFEIKGSNMDERKIEEAISLLKKELE..................................................................................... 404
7 -86.8004fek_A mol:protein length:262 Putative diflavin flavoprotein A 5  ali model follow..  23  10QVLPIATNTKVLRARSWSRLRFEI-EYALERGTTSNSYVIEGDKTAIIDPPVESFMKIYLEALQQTVNLKKLDYVILGHFSPNRIPTFKALLELAPQITFVCSLPAAGDLRAAFLNILPMRGKETLDLGKGHVLKFLPIPSPRWPAGLCTYDVQTQILYTDKIFGAHICGDDVFDDNWE--SFKEDQRYYFNCLMAPHAIHVEAALEKIS--DLQVRLYAVGHGPLVRTSLIALTQAYADWSKAQKLE................................................................................................................................................................................................................................... 256
8 -47.2003hly_A mol:protein length:161 Flavodoxin-like domain  ali model follow..  19  2........................................................................................................................................................................................................................................................SVLIGYLSDYGYSDRLSQAIGRGLVKTG--VAVEMVDLRAVDPQELIEAVSSARGIVLGTPPSQPS--EAVATALSTIFAAAHNKQAIGLFDSYGGDDEPIDALLAQFRNLGLHTAPPIRVKDQPTEAIYQQCEESGTDLGQWLTRADAIQTMKS........................................................................ 153
9 -47.2003fni_A mol:protein length:159 Putative diflavin flavoprotein A 3  ali model follow..  22  1...................................................................................................................................................................................................................................................TKAETSIGVFYVSEYGYSDRLAQAIINGITKTG--VGVDVVDLGAVDLQELRELVGRCTGLVIGMSPAASA--ASIQGALSTILGSVNEKQAVGIFETGGGDDEPIDPLLSKFRNLGLTTAPAIRIKQTPTENTYKLCEEAGTDLGQWVTRDRLE............................................................................. 153
10 -33.8001s24_A mol:protein length:87 Rubredoxin 2  ali model follow..  19  2...................................................................................................................................................................................................................................................................................................................................................................................................TSLEKLPSADVKGQDLYKTQPPRSDAQGGKAYLKWICITCGHIYDEALGDEAEGFTPGTRFEDIPDDWCCPDCGATKEDYVLYEEK.. 87
11 -33.6002kn9_A mol:protein length:81 Rubredoxin  ali model follow..  27  2.................................................................................................................................................................................................................................................................................................................................................................................................................AMGTLEAQTQGPGSMNDYKLFRCIQCGFEYDEALGWPEDGIAAGTRWDDIPDDWSCPDCGAAKSDFEMVEVARS 75
12 -31.6002q0j_A mol:protein length:321 Quinolone signal response protein  ali model follow..  14  6.SGLVPRGSHMLGQLDDDLCLLGD--------VQVPVFLLREASWALVEGGISRDAELVWADLCRWADPSQVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQAWKSES-PVRAVADGEWLELGPRHRLQVIEAH--HSDDHVVFYDVRRRRLFCGDALGEFDEAEGVWRPLVFDD------------------EAYLESLERLQRLP-TLLQLIPGHGGLLRGRLAA--GAESAYTECLRLCRRLLWRQSMGESLDELSEELHRAWGGQ--SVDFLPGELHLGSMRRMLEILSRQA............................................................................................................................................................................. 311
13 -29.1001dx8_A mol:protein length:70 RUBREDOXIN  ali model follow..  31  4.................................................................................................................................................................................................................................................................................................................................................................................................................................DEGKYECEACGYIYEPEKGDKFAGIPPGTPFVDLSDSFMCPACRSPKNQFKSIKKVIA 61
14 -28.9001fln_A mol:protein length:138 FLAVODOXIN  ali model follow..  27  1.........................................................................................................................................................................................................................................................MKIVYWSGTGNTEKMAELIAKGIIESG--KDVNTINVSDVNIDELLN----EDILILGCSAMGPEVLESEFEPFIEEISTKISGKKVALFGSYGWGGKWMRDFEERMNGYGCVVVTPLIVQNEPD-EAEQDCIEFGKKIAN..................................................................................... 137
15 -28.6002pvx_A mol:protein length:54 Rubredoxin  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKWVCTVCGYIYDEDAGDPDNGISPGTKFEELPDDWVCPLCGVGKDQFEKLED... 54
16 -28.5001smm_A mol:protein length:54 Rubredoxin  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPACGVGKDQFEEVEE... 54
17 -28.5004rxn_A mol:protein length:54 RUBREDOXIN  ali model follow..  45  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYDPEDGDPDDGVNPGTDFKDIPDDWVCPLCGVGKDEFEEVEE... 54
18 -28.5001t9q_A mol:protein length:54 Rubredoxin  ali model follow..  45  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGLGKDQFEEVEE... 54
19 -28.5001b2o_A mol:protein length:54 PROTEIN (RUBREDOXIN)  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCVYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCAVGKDQFEEVEE... 54
20 -28.5001c09_A mol:protein length:54 RUBREDOXIN  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGAGKDQFEEVEE... 54
21 -28.5001be7_A mol:protein length:54 RUBREDOXIN  ali model follow..  41  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLSGVGKDQFEEVEE... 54
22 -28.5001b13_A mol:protein length:54 PROTEIN (RUBREDOXIN)  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCAYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEE... 54
23 -28.5001b2j_A mol:protein length:54 PROTEIN (RUBREDOXIN)  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCAVGKDQFEEVEE... 54
24 -28.5001t9p_A mol:protein length:54 Rubredoxin  ali model follow..  41  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGAPKDQFEEVEE... 54
25 -28.5001t9o_A mol:protein length:54 Rubredoxin  ali model follow..  43  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPLCGGGKDQFEEVEE... 54
26 -28.4002pve_A mol:protein length:54 Rubredoxin  ali model follow..  37  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYTCKICGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCPICGAPKSEFEEVEE... 54
27 -28.4002v3b_B mol:protein length:55 RUBREDOXIN 2  ali model follow..  40  2...................................................................................................................................................................................................................................................................................................................................................................................................................................RKWQCVVCGFIYDEALGLPEEGIPAGTRWEDIPADWVCPDCGVGKIDFEMIE.... 53
28 -28.4001bq8_A mol:protein length:54 PROTEIN (RUBREDOXIN)  ali model follow..  37  2...................................................................................................................................................................................................................................................................................................................................................................................................................................AKWVCKICGYIYDEDAGDPDNGISPGTKFEELPDDWVCPICGAPKSEFEKLED... 54
29 -28.4001iu5_A mol:protein length:53 rubredoxin  ali model follow..  39  1...................................................................................................................................................................................................................................................................................................................................................................................................................................AKYVCKICGYIYDEDAGDPDNGVSPGTKFEEIPDDWVCPICGAPKSEFEKLED... 53
30 -28.3001yk5_A mol:protein length:53 Rubredoxin  ali model follow..  34  2...................................................................................................................................................................................................................................................................................................................................................................................................................................AKWRCKICGYIYDEDEGDPDNGISPGTKFEDLPDDWVCPLCGAPKSEFERIE.... 53
31 -28.3001yk4_A mol:protein length:52 Rubredoxin  ali model follow..  34  1...................................................................................................................................................................................................................................................................................................................................................................................................................................AKLSCKICGYIYDEDEGDPDNGISPGTKFEDLPDDWVCPLCGAPKSEFERIE.... 52
32 -28.3001qcv_A mol:protein length:53 PROTEIN (RUBREDOXIN VARIANT PFRD-XC4)  ali model follow..  30  1...................................................................................................................................................................................................................................................................................................................................................................................................................................AKWVLKITGYIYDEDAGDPDNGISPGTKFEELPDDWVAPITGAPKSEFEKLED... 53
33 -28.3001rdv_A mol:protein length:52 RUBREDOXIN  ali model follow..  41  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYVCTVCGYEYDPAEGDPDNGVKPGTAFEDVPADWVCPICGAPKSEFEPA..... 52
34 -28.2002pya_A mol:protein length:52 Rubredoxin  ali model follow..  34  1...................................................................................................................................................................................................................................................................................................................................................................................................................................AKLSCKICGYIYDEDEGDPDNGISPGTKFEDLPDDWVCPLCGSPKSEFERIE.... 52
35 -28.2001rb9_A mol:protein length:52 RUBREDOXIN  ali model follow..  39  2...................................................................................................................................................................................................................................................................................................................................................................................................................................KKYVCTVCGYEYDPAEGDPDNGVKPGTSFDDLPADWVCPVCGAPKSEFEAA..... 52
36 -27.7001e8j_A mol:protein length:52 RUBREDOXIN  ali model follow..  44  2...................................................................................................................................................................................................................................................................................................................................................................................................................................DIYVCTVCGYEYDPAKGDPDSGIKPGTKFEDLPDDWACPVCGASKDAFEK...... 51
37 -26.5002m4y_A mol:protein length:56 Rubredoxin  ali model follow..  37  2...................................................................................................................................................................................................................................................................................................................................................................................................................................TAYRCPVCDYTYDEGKGDPREGFPAGTRWDQIPDDWCCPDCSVRKVDFERMGGK.. 56
38 -26.2002fax_A mol:protein length:138 FLAVODOXIN  ali model follow..  25  1.........................................................................................................................................................................................................................................................MKIVYWSGTGNTEKMAELIAKGIIESG--KDVNTINVSDVNIDELLN----EDILILGCSAMGDEVLEESEEPFIEEISTKISGKKVALFGSYGWGGKWMRDFEERMNGYGCVVVETPLIVQNEPDEAEQDCIEFGKKIAA..................................................................................... 137
39 -23.5001fla_A mol:protein length:138 FLAVODOXIN  ali model follow..  23  1.........................................................................................................................................................................................................................................................MKIVYWSGTGNTEKMAELIAKGIIESGKDVNTINVS------DVNIDELLNEDILILGCSAMDDEVLEEFEPFIEEIST-KISGKKVALFGSYGWGGKWMRDFEERMNGYGCVVVETPLIVQNEPDEAEQDCIEFGKKIAN..................................................................................... 137
40 -23.5002fz5_A mol:protein length:137 Flavodoxin  ali model follow..  22  2.........................................................................................................................................................................................................................................................VEIVYWSGTGNTEAMANEIEAAVKAAGADVESVRFEDTNVD------DVASKDVILLGCPAMGSEELEDVEPFFTDLAP-KLKGKKVGLFGSYGWGGEWMDAWKQRTEDTGATVIGTAIVNEMP--DNAPECKELGEAAAKA.................................................................................... 137
41 -21.9003kap_A mol:protein length:147 Flavodoxin  ali model follow..  17  1.......................................................................................................................................................................................................................................................SKVLILFGSSTGNTESIAQKLEELVAAGG--HEVTLLNAAEASADNLADG---YDAVLMGCSAWGMELQDDFAPLFDEMENMGLKGKKLAAFASGDMECGAVPAIEEKARGLGAEVICEGLKIEGDASSDPDAVSAFAEDVLKKL................................................................................... 147
42 -21.7006rxn_A mol:protein length:46 RUBREDOXIN  ali model follow..  35  1.................................................................................................................................................................................................................................................................................................................................................................................................................................XMQKYVCNVCGYEYDPAEHD-------NVPFDQLPDDWCCPVCGVSKDQFSPA..... 46
43 -21.6001sml_A mol:protein length:269 PROTEIN (PENICILLINASE)  ali model follow..  14  24..LQIADHTWQIGT------------------EDLTALLVQPDGAVLLDGGMPQMASHLLDNMKARVTPRDLRLILLSHAHADHAGPVAELKRRT-GAKVAANAESAVLLARGGSD-RIVMDGEVITVGGI-VFTAHFMA--HTPGSTAWTWTDTRNGKPVRI---------AYADSLSAPGYQLQGNPRYPHLIEDY----RRSFATVRA--LPCDVLLTPHPGASNWDYAAGARAGAKALTCKA----------ADAAEQKFDGQLAKETAGA........................................................................................................................................................................................................ 268
44 -21.4003f6r_A mol:protein length:148 Flavodoxin  ali model follow..  17  2.......................................................................................................................................................................................................................................................SKVLIVFGSSTGNTESIAQKLEELIAAGG--HEVTLLNAADASAENLADG---YDAVLFGCSAWGMEDLEDFLSLFEEFDRIGLAGRKVAAFASGDQECGAVPAIEERAKELGATIIAEGLKMEGDASNDPEAVASFAEDVLKQL................................................................................... 148
45 -21.3003adr_A mol:protein length:261 Putative uncharacterized protein ST1585  ali model follow..  18  21...................................TVYVMCGEKTVMIDA----------NSIADFSFLDKLDYIVLTHLHIDHIGLLPELLQV-YKAKVLVKSGFKKYLTSED-KVIEVEGNEEFDLG-GYRMRLIYTP--HARHHMSVLV--DDFLFTGDSAGA-----------------------YFNGVVIPTTPMYMESLKRQ--IELKPKVVGFAHGLVSPKIMEEHLKQMLSKEE------IQINVDIGGVAGEILRKQIEVNLRG......................................................................................................................................................................................................... 253
46 -20.9004p62_A mol:protein length:295 Metallo-beta-lactamase AIM-1  ali model follow..  16  43.PQKVYGNTWYVGT------------------CGISALLVTDAGHILVDAATPQAGPQILANIRALFRPEDVRAIVLSHEHFDHAGSLAELQKAT-GAPVYARAPAIDTLKRGLPD-VTLADDGVVSVGPL-ALTAVASP--HTPGGTSWTWRDCRQMVYADSLTAISDDVYRYSDDAAHPGYLAAFRNTLARV-----------------AALDCDILVTPHPSASG-------------RIGPRAAAPLMDTTACRRYAQGARQRLEKRLAEE........................................................................................................................................................................................................ 292
47 -20.9005iqk_A mol:protein length:271 beta-lactamase Rm3  ali model follow..  14  17..FRLFGNTYYVGMKG------------------LSSVLVTPQGHVLIDGGLPESAPKIIANIGALFRIEDVKLILNSHGHIDHAGGLAELQRRS-NALVAASPSAALDLASGEVG-RLARDGGQFNVGP-VYLTAHATP--HTPGGLSWTWQSCD-MVYADSINAVSRPGFKFSASSEYPNALADLRHSFETL-----------------EKLPCDVLISAHP-----EASQLWQRLEASATGGSDA--FVDPQACRAYVAAARTLLDSRLDQEKQQ..................................................................................................................................................................................................... 271
48 -20.7003lvz_A mol:protein length:294 Blr6230 protein  ali model follow..  17  41..FQLIDNIYYVGT------------------DGIAVYVIKSQGLILMDTAMPQSTGMIKDNIAKLFKVADIKLILNTHAHLDHTGGFAEIKKET-GAQLVAGERDKPLLEGGYYP-RAVKEGDRVTLGDT-TLTAHATP--HSPGCTSWEMTVKDGKEDREV---------LFFCSGTVALNRLVGQPTYAGIVDDY----RATFAKAKA--MKIDVLLGPHPEVYGMQAKR--------EMKDGAPNPFIKPGELVTYATSLSEDFDKQLAKQTAALEKK................................................................................................................................................................................................. 294
49 -20.7003l6n_A mol:protein length:219 metallo-beta-lactamase  ali model follow..  17  7IEPPIKNNLH----------IYKTFGVFGGKEYSANSYLVTKKGVVLFDVPWEKVQYQSLMDTIKKRHNLPVVAVFATHSHDDRAGDLSFFNNK--GIKTYATAKTNEFLKKDGKATEIIKTGKPYRIG-GEEFVVDFLGEGHTADNVVVWFPKYNVLDGGCLVKSNSATDLGYIKEANVEQW-------------------PKTINKLKAKYSKATLIIPGHDEWKGGGHVEHTLELLN........................................................................................................................................................................................................................................... 217
50 -20.5005a87_A mol:protein length:248 METALLO-BETA-LACTAMASE VIM-5  ali model follow..  13  29..YQIADGVW----------SHIATQSFDGAVYPSNGLIVRGDELLLIDTWGAKNTAALLAEIEKQIG-LPVTRAVSTHFHDDRVGGVDVLRKA--GVATYASPSTRRLAEAEGNEIGLSSSGDAVRFGP---VELFYPGAAHSTDNLVVYVPSANVLYGGCAVLALSRTSAGNVADADLAEW-------------------PTSVERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVTAHKNRSVAE.................................................................................................................................................................................................................................. 248
51 -20.5002nze_A mol:protein length:222 Beta-lactamase II  ali model follow..  14  14..SQLNKNVW----------VHTELGSFNGEAVPSNGLVLNSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHADHIGGIKTLKER--GIKAHSTALTAELAKGYEEPLGDLQTVTNLKFG-NMKVETFYPGKGHTEDNIVVWLPQYNILVGGSL-------------------VKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK........................................................................................................................................................................................................................................... 222
52 -20.5003vpe_A mol:protein length:262 Metallo-beta-lactamase  ali model follow..  14  12..FTIYGNTHYVGTGG------------------ISAVLLSPQGHILVDGTTEKGAQVVAANIRAMFKLSDVKYILSTHSHEDHAGGISAMQKLT-GATVLAGAANVDTLRTGVSP-RAVADGELVKLGP--AVKAHATP--HTEGGITWTWQSCEQGKCKDV---------VFADSLTAVSADSYRFSDHPEVVASLRGSFEAVEK------LSCDIAIAAHP-----EVNDMWTRQQRAAKEGNSA--YVDNGACRAIAAAGRKRLETRLASE........................................................................................................................................................................................................ 260
53 -20.4004awy_B mol:protein length:303 METALLO-BETA-LACTAMASE AIM-1  ali model follow..  19  43.PLKVYGNTWYVGT------------------CGISALLVTDAGHILVDAATPQAGPQILANIRALFRPEDVRAIVFSHEHFDHAGSLAELQKAT-GAPVYARAPAIDTLKRGLPD-VTLADDGVVSVGPL-ALTAVASP--HTPGGTSWTWRDCRQMVYADSLTAISDDVFRYSDDAAHPGYLAAFRNTLARV-----------------AALDCDILVTPHP........................................................................................................................................................................................................................................................... 251
54 -20.4001m2x_A mol:protein length:223 class B carbapenemase BlaB-1  ali model follow..  11  6...KLKDNLY----------VYTTYNTFNGTKYAANAYLVTDKGVVVIDCPWGEDKFKSFTDEIYKKHGKKVIMNIATHSHDDRAGGLEYFGKI--GAKTYSTKMTDSILAKENKPRYTFDNNKSFKVG-KSEFQVYYPGKGHTADNVVVWFPKEKVLVGGCIIKSADSKDLGYIGEAYVNDWT-------------------QSVHNIQQKFSGAQYVVAGHDDWKDQRSIQHTLDLINEYQQKQKAS.................................................................................................................................................................................................................................. 222
55 -20.3002uyx_A mol:protein length:228 BETA-LACTAMASE II  ali model follow..  13  20..SQLNKNVW----------VHTELGSFNGEAVPSNGLVLNSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDVIITHAHASRIGGIKTLKER--GIKAHSTALTAELAKGYEEPLGDLQTVTNLKFG-NMKVETFYPGKGHTEDNIVVWLPQYNILVGGCL-------------------VKSTSAKDLGNVADAYVNEWSTSIENVLKRYRNINAVVPGHGEVGDKGLLLHTLDLLK........................................................................................................................................................................................................................................... 228
56 -20.1001jt1_A mol:protein length:263 FEZ-1, class B3 metallo-beta-lactamase  ali model follow..  14  10.PFRIAGNLYYVGTDD------------------LASYLIVTPRNILINSDLEANVPMIKASIKKLFKFSDTKILLISHAHFDHAAGSELIKQQT-KAKYMVMDEDVSVILSGGKS-KVLHDGERVELGG-TVLTAHLTP--HTRGCTTWTMKLKDHGKQYQAVIIGSIGVNPGYKLVDNITYPKIAEDY------------KHSIKVLES--MRCDIFLGSHAGMFD--------KNKYVLLSKGQNNPFVDPTGCKNYIEQKANDFYTELKKQ........................................................................................................................................................................................................ 260
57 -20.0004heq_A mol:protein length:146 Flavodoxin  ali model follow..  24  2.......................................................................................................................................................................................................................................................PKALIVYGSTTGNTEGVAEAIAKTLNSEG--METTVVNVADVTAPGLAEG---YDVVLLGCSTWGDDEIEDFVPLYEDLDRAGLKDKKVGVFGSYTYFCGAVDVIEKKAEELGATLVSSLKIDGEPDSAEVLDAREVLARV....................................................................................... 146
58 -19.7003fcz_A mol:protein length:222 Beta-lactamase 2  ali model follow..  13  14..SQLNKNVW----------VHTELGSFNGEAVPSSGLVLNSKGLVLVDSSWDDKLTKELIEMVEKKFQKRVTDAIITHAHADRIGGIKTLKER--GIKAHSTALTAELAKGYEEPLGDLQTVTNLKFG-NMKVETFYPGKGHTEDNIVVWLPQYNILVGGCL-------------------VKSTSAKDLGNVADAYVNEWSTSIENVSKRYRNINAVVPSHGEVGDKGLLLHTLDLLK........................................................................................................................................................................................................................................... 222
59 -19.7001a7t_A mol:protein length:232 METALLO-BETA-LACTAMASE  ali model follow..  13  14..TQLSDKVY--------TYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTEMLVNWVTDSLHAKVTTFIPNHWHGDCIGGLGYLQRK--GVQSYANQMTIDLAKEKGLPVHGFTDSLTVSLD-GMPLQCYYLGGGHATDNIVVWLPTENILFGGCMLKDNQTTSIGNISDADVTAW-------------------PKTLDKVKAKFPSARYVVPGHGNYGGTELIEHTKQIVNQYIESTSK................................................................................................................................................................................................................................... 231
60 -19.7001znb_A mol:protein length:232 METALLO-BETA-LACTAMASE  ali model follow..  13  14..TQLSDKVY--------TYVSLAEIEGWGMVPSNGMIVINNHQAALLDTPINDAQTETLVNWVADSLHAKVTTFIPNHWHGDCIGGLGYLQKK--GVQSYANQMTIDLAKEKGLPVHGFTDSLTVSLD-GMPLQCYYLGGGHATDNIVVWLPTENILFGGCM-------------------LKDNQATSIGNISDADVTAWPKTLDKVKAKFPSARYVVPGHGDYGGTELIEHTKQIVNQYIESTSK................................................................................................................................................................................................................................... 231
61 -19.5005aeb_A mol:protein length:272 LRA-12  ali model follow..  13  24..FRIAGNLYYIGTYD-------------------ACYLITTKQNIIVNTGLAASALQIKNNIKALFKLTDTKILLTTQAHYDHLGAMAEIKKIT-GAKLMADEGDATVMADGGSS-RLLHDKDTIQLGD--KLVMLHHP--HTKGSCSFLFDTKRILIANMP-------TIVIEKKFSEVSSYPGIAKDY-----------AYTLQAMKN--LSFDIWVASHA-----SQFSMHSKHKP--GDGYNPKSFMDRKGYDESLDKLQKEYEKHLNEN........................................................................................................................................................................................................ 272
62 -19.3004uwo_B mol:protein length:266 METALLO-BETA-LACTAMASE VIM-26  ali model follow..  14  47..YQIADGVW----------SHIATQSFDGAVYPSNGLIVRGDELLLIDTWGAKNTAALLAEIEKQIG-LPVTRAVSTHFHDDRVGGVDVLRAA--GVATYASPSTRRLAEAEGNEIGLSSSGDAVRFGP---VELFYPGAAHSTDNLVVYVPSANVLYGGCA-------------------VLELSSTSAGNVADADLAEWPTSVERIQKHYPEAEVVIPGHGLPGGLDLLQHTANVVKAHKNRSVAE.................................................................................................................................................................................................................................. 266
63 -19.1002y87_A mol:protein length:265 METALLO-B-LACTAMASE  ali model follow..  15  46..YKIGDGVW----------SHIATQKLGDTVYSSNGLIVRADELLLIDTWGAKNTVALLAEIEKQIG-LPVTRSISTHFHDDRVGGVDVLRAA--GVATYTSPLTRQLAEAAGNEVALSSSGDVVRFGP---VEVFYPGAAHSGDNLVVYVPAVRVLFGGCA-------------------VHEASRESAGNVADANLAEWPATIKRIQQRYPEAEVVIPGHGLPGGLELLQHTTNVVKTHKVRPVAE.................................................................................................................................................................................................................................. 265
64 -19.1002yz3_A mol:protein length:266 Metallo-beta-lactamase  ali model follow..  14  47..YQIADGVW----------SHIATQSFDGAVYPSNGLIVRDDELLLIDTWGAKNTAALLAEIEKQIG-LPVTRAVSTHFHDDRVGGVDVLRAA--GVATYASPSTRRLAEVEGNEIGLSSSGDAVRFGP---VELFYPGAAHSTDNLVVYVPSASVLYGGCAIYELSRTSAGNVADADLAEW-------------------PTSIERIQQHYPEAQFVIPGHGLPGGLDLLKHTTNVVKAHTNRSVVE.................................................................................................................................................................................................................................. 266
65 -18.8004gyq_A mol:protein length:243 Beta-lactamase NDM-1  ali model follow..  12  25..RQLAPNVWHTSYLDMP---------GFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGMVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCL-------------------IKDSKAKSLGNLGAADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR........................................................................................................................................................................................................................................ 243
66 -18.8003spu_A mol:protein length:265 Beta-lactamase NDM-1  ali model follow..  11  26..RQLAPNVWHTSYLDMP---------GFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGMVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHY-------------------AASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRKLVPRGS................................................................................................................................................................................................................................. 251
67 -18.7003q6v_A mol:protein length:233 Beta-lactamase  ali model follow..  14  10...HFKGPLY---------------IVEDKEYVQENSVYIGTDGITIIGATWTPETAETLYKEIRKVSPLPINEVINTNYHTDRAGGNAYWKTL--GAKIVATQMTYDLQKSQWGSIVNFTRPGDFNLQNG-SIRAMYLGEAHTKDGIFVYFPAERVLYGNCI-------------------LKENLGNMSFANRTEYPKTLEKLKGLIEQGELKVDSIIAGHDTPIHD--VGLIDHYLTLLEKAPK.................................................................................................................................................................................................................................... 233
68 -18.7004tyf_A mol:protein length:231 NDM-4  ali model follow..  12  13..RQLAPNVWHTSYLDMP---------GFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGLVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCL-------------------IKDSKAKSLGNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR........................................................................................................................................................................................................................................ 231
69 -18.6004rl2_A mol:protein length:246 Beta-lactamase NDM-1  ali model follow..  12  28..RQLAPNVWHTSYLDMP---------GFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGMVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHY-------------------AASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR........................................................................................................................................................................................................................................ 246
70 -18.5005a5z_A mol:protein length:251 BETA-LACTAMASE NDM-1  ali model follow..  12  25..RQLAPNVWHTSYLD----------MPGFGAVASNGLIVRGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGMVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHY-------------------AASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLRLE...................................................................................................................................................................................................................................... 245
71 -18.4001akq_A mol:protein length:147 FLAVODOXIN  ali model follow..  18  1.......................................................................................................................................................................................................................................................PKALIVYGSTTGNTEYTAETIARELADAG--YEVDSRDAASVEAGGLFEG---FDLVLLGCSTWGDDLQDDFIPLFDSLEETGAQGRKVACFGCYEYFCGAVDAIEEKLKNLGAEIVDGLRIDGDPRAAR-DDIVGWAHDVRGAI................................................................................... 147
72 -18.4003rkk_A mol:protein length:237 Beta-lactamase NDM-1  ali model follow..  12  19..RQLAPNVWHTSYLD----------MPGFGAVASNGLIVRGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTHAHQDKMGGMDALHAA--GIATYANALSNQLAPQEGMVAGWVEPATAPNFGP---LKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHY-------------------AASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR........................................................................................................................................................................................................................................ 237
73 -18.4002ynt_B mol:protein length:233 GIM-1 PROTEIN  ali model follow..  12  10..IKIEDGVY--------LHTSFKNIEGYGLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDRG-YQVMASISTHSHEDRTAGIKLLNSK--SIPTYTSELTKKLLAREGKPVPTHYKDDEFTLG-NGLIELYYPGAGHTEDNIVAWLPKSKILFGGCLVRSHEWEALGYVGDASISSW-------------------ADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASNKLMQPT................................................................................................................................................................................................................................. 227
74 -18.2001f4p_A mol:protein length:147 FLAVODOXIN  ali model follow..  18  1.......................................................................................................................................................................................................................................................PKALIVYGSTTGNTEYTAETIARELADAG--YEVDSRDAASVEAGGLFEG---FDLVLLGCSTWGDDLQDDFIPLFDSLEETGAQGRKVACFGCWEYFCGAVDAIEEKLKNLGAEIVDGLRIDGDPRAAR-DDIVGWAHDVRGAI................................................................................... 147
75 -18.1005acp_A mol:protein length:250 GIM-1 PROTEIN  ali model follow..  12  27..IKIEDGVY--------LHTSFKNIEGYGLVDSNGLVVLDNNQAYIIDTPWSEEDTKLLLSWATDRG-YQVMASISTHSHEDRTAGIKLLNSK--SIPTYTSELTKKLLAREGKPVPTHYKDDEFTLG-NGLIELYYPGAGHTEDNIVAWLPKSKILFGGCLVRSHEREGLGYVGDASISSW-------------------ADSIKNIVSKKYPIQMVVPGHGKVGSSDILDHTIDLAESASNKLMQPT................................................................................................................................................................................................................................. 244

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Alexey M. Eroshkin, Andrew LeBlanc, Dana Weekes, Kai Post, Zhanwen Li, Akhil Rajput, Sal T. Butera, Dennis R. Burton, Adam Godzik. bNAber: database of broadly neutralizing HIV antibodies. Nucl. Acids Res. 2013; published on November 7, 2013.

Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci. 2002 Jul;11(7):1702-13.